|
Symbol Name ID |
Crebbp
CREB binding protein MGI:1098280 |
| * | Aspects of the system are reported to show a normal phenotype. |
| Darker colors indicate more annotations |
| Human Phenotypes | Feeding difficulties |
Feeding difficulties in infancy |
Autistic behavior |
Autism |
Hyperactivity |
Attention deficit hyperactivity disorder |
Impulsivity |
Self-mutilation |
Phonophobia |
| Disease(s) Associated with CREBBP | |||||||||
| Rubinstein-Taybi syndrome |
| Mouse Phenotypes | behavior/neurological phenotype |
abnormal behavior |
abnormal contextual conditioning behavior |
impaired long-term object recognition memory |
abnormal spatial learning |
decreased aggression towards male mice |
decreased anxiety-related response |
increased thigmotaxis |
increased grooming behavior |
impaired coordination |
decreased grip strength |
decreased vertical activity |
increased vertical activity |
decreased locomotor activity |
increased locomotor activity |
increased stereotypic behavior |
abnormal nest building behavior |
abnormal social investigation |
seizures |
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| Availability | Mouse Genotype | |||||||||||||||||||
| Crebbptm2Pkb/Crebbptm2Pkb | ||||||||||||||||||||
| CrebbpGt(U-San)112Imeg/Crebbp+ | ||||||||||||||||||||
| Tg(Camk2a-Crebbp*)1364Tabe/0 | * | |||||||||||||||||||
| Crebbptm1.2Ltz/Crebbptm1.2Ltz Tg(Camk2a-cre)T29-1Stl/0 (conditional) |
* | |||||||||||||||||||
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/16/2024 MGI 6.23 |
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