Symbol
Name
ID

Adam17
a disintegrin and metallopeptidase domain 17
MGI:1096335

Phenotype annotations related to vision/eye

Darker colors indicate more annotations

Mouse Phenotypes

absent Meibomian glands

increased incidence of corneal inflammation

abnormal eye morphology

abnormal anterior eye segment morphology

abnormal canal of Schlemm morphology

absent Schlemm's canal

anterior iris synechia

abnormal conjunctival sac morphology

abnormal cornea morphology

absent Descemet membrane

decreased cornea thickness

absent corneal endothelium

abnormal corneal epithelium morphology

corneal opacity

corneal scarring

lens vacuoles

aphakia

cataract

failure of eyelid fusion

microphthalmia

abnormal eyelid margin morphology

early eyelid opening

eyelids open at birth

abnormal retina morphology

anophthalmia

eye opacity

Availability

Mouse Genotype

Adam17^tm1.1Bbl/Adam17^tm1.1Bbl

Adam17^tm1.1Srj/Adam17^tm1.1Srj

Adam17^tm1.2Wesh/Adam17^tm1.2Wesh

Adam17^tm1Imx/Adam17^tm1Imx

Adam17^woe/Adam17^woe

Adam17^tm1Imx/Adam17^woe

Adam17^tm1.2Bbl/Adam17^tm1.2Bbl
Sox9^tm3(cre)Crm/Sox9⁺ (conditional)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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