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Symbol
Name
ID
Adam17
a disintegrin and metallopeptidase domain 17
MGI:1096335
Phenotype annotations related to growth/size/body
Darker colors indicate more annotations
Human Phenotypes
Increased waist to hip ratio
Disease(s) Associated with ADAM17
type 2 diabetes mellitus

Mouse Phenotypes
increased heart weight
enlarged heart
enlarged esophagus
decreased body weight
weight loss
increased body weight
nuchal edema
decreased body length
increased susceptibility to weight loss
decreased body size
postnatal growth retardation
decreased fetal weight
enlarged spleen
Availability Mouse Genotype
Adam17m1Btlr/Adam17m1Btlr
Adam17tm1.1Srj/Adam17tm1.1Srj
Adam17tm1.2Rain/Adam17tm1.2Rain
Adam17tm1Imx/Adam17tm1Imx
Adam17woe/Adam17woe
Adam17tm1a(EUCOMM)Wtsi/Adam17+
Adam17tm1.1Wesh/Adam17tm1.1Wesh
Nkx2-5tm1(cre)Rjs/Nkx2-5+  (conditional)
Adam17tm1.2Bbl/Adam17tm1.2Bbl
Sox9tm3(cre)Crm/Sox9+  (conditional)
Adam17tm1.1Rain/Adam17tm1.2Rain
Tg(Tek-cre)12Flv/0  (conditional)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/30/2024
MGI 6.23
The Jackson Laboratory