Symbol Name ID |
Tnfrsf11b
tumor necrosis factor receptor superfamily, member 11b (osteoprotegerin) MGI:109587 |
Darker colors indicate more annotations |
Human Phenotypes | Sensorineural hearing impairment |
Hearing impairment |
Disease(s) Associated with TNFRSF11B | ||
Paget's disease of bone 5 |
Mouse Phenotypes | otosclerosis |
abnormal middle ear ossicle morphology |
abnormal incus body morphology |
abnormal malleus morphology |
abnormal stapes morphology |
abnormal stapes annular ligament morphology |
abnormal stapes footplate morphology |
abnormal inner ear morphology |
abnormal otic capsule morphology |
abnormal middle ear morphology |
abnormal auditory brainstem response |
increased or absent threshold for auditory brainstem response |
increased or absent distortion product otoacoustic emission threshold |
absent distortion product otoacoustic emissions |
increased susceptibility to age-related hearing loss |
deafness |
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Availability | Mouse Genotype | ||||||||||||||||
Tnfrsf11bem1(IMPC)Mbp/Tnfrsf11bem1(IMPC)Mbp | |||||||||||||||||
Tnfrsf11btm1Khs/Tnfrsf11btm1Khs |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/16/2024 MGI 6.23 |
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