|
Symbol Name ID |
Pten
phosphatase and tensin homolog MGI:109583 |
| * | Aspects of the system are reported to show a normal phenotype. |
| Darker colors indicate more annotations |
| Human Phenotypes | Autistic behavior |
Autism |
Attention deficit hyperactivity disorder |
| Disease(s) Associated with PTEN | |||
| macrocephaly-autism syndrome |
| Mouse Phenotypes | behavior/neurological phenotype |
abnormal behavior |
lethargy |
abnormal behavioral response to xenobiotic |
impaired spatial learning |
abnormal response to novel odor |
polyphagia |
decreased aggression towards male mice |
increased anxiety-related response |
increased thigmotaxis |
fast extinction of fear memory |
increased startle reflex |
ataxia |
enhanced coordination |
impaired balance |
hunched posture |
decreased locomotor activity |
increased locomotor activity |
hindlimb paralysis |
increased stereotypic behavior |
abnormal maternal nurturing |
abnormal nest building behavior |
abnormal sexual interaction |
abnormal social investigation |
seizures |
tonic-clonic seizures |
abnormal spike wave discharge |
sporadic seizures |
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| Availability | Mouse Genotype | ||||||||||||||||||||||||||||
| Ptentm1.1Yxy/Ptentm1.1Yxy | * | ||||||||||||||||||||||||||||
| Ptentm1Engc/Ptentm1Engc | |||||||||||||||||||||||||||||
| Ptentm1Rps/Pten+ | |||||||||||||||||||||||||||||
| Tg(Pten)1Srn/0 | |||||||||||||||||||||||||||||
| Ptentm1Hwu/Ptentm1Hwu Tg(Gfap-cre)77.6Mvs/0 (conditional) |
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| Ptentm1Hwu/Ptentm1Hwu Slc6a3tm1.1(cre)Bkmn/Slc6a3+ (conditional) |
* | ||||||||||||||||||||||||||||
| Gt(ROSA)26Sortm9(cre/ESR1)Arte/Gt(ROSA)26Sor+ Ptentm1Hwu/Ptentm1Hwu (conditional) |
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| Ptentm1Mro/Ptentm1Mro Tg(En2-cre)22Alj/0 (conditional) |
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| Ptentm2Mak/Ptentm2Mak Tg(Gfap-cre)1Sbk/0 (conditional) |
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| Ptentm2Mak/Ptentm2Mak Tg(Cyp1a1-cre)1Dwi/0 (conditional) |
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| Ptentm2Mak/Ptentm2Mak Tg(Col2a1-cre)1Xya/? (conditional) |
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| Ptentm2Mak/Ptentm2Mak Tg(Eno2-cre)39Jme/0 (conditional) |
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| Ptentm2Mak/Ptentm2Mak Tg(Nes-cre/ERT2,-ALPP)1Sbk/0 (conditional) |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/16/2024 MGI 6.23 |
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