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Symbol
Name
ID

Smn1
survival motor neuron 1
MGI:109257

Phenotype annotations related to mortality/aging

Darker colors indicate more annotations

Human Phenotypes	Death in childhood
Disease(s) Associated with SMN1	Death in childhood
Werdnig-Hoffmann disease

Mouse Phenotypes		premature death	lethality throughout fetal growth and development, complete penetrance	embryonic lethality during organogenesis, complete penetrance	embryonic lethality during organogenesis, incomplete penetrance	embryonic lethality before implantation, complete penetrance	embryonic lethality between implantation and somite formation, complete penetrance	embryonic lethality, complete penetrance	prenatal lethality, complete penetrance
Availability	Mouse Genotype	premature death						embryonic lethality, complete penetrance	prenatal lethality, complete penetrance
	Smn1^tm1.1Jme/Smn1^tm1.1Jme
	Smn1^tm1Cdid/Smn1^tm1Cdid
	Smn1^tm1Hung/Smn1^tm1Hung
	Smn1^tm1Msd/Smn1^tm1Msd
	Smn1^tm2Cdid/Smn1^tm2Cdid
	Smn1^tm2Mrph/Smn1^tm2Mrph
	Smn1^{tm3(SMN2/Smn1)Mrph}/Smn1^{tm3(SMN2/Smn1)Mrph}
	Smn1^{tm4(SMN2)Mrph}/Smn1^{tm4(SMN2)Mrph}
	Smn1^tm1Msd/Smn1^tm1Rako
	Smn1^tm2Mrph/Smn1^{tm4(SMN2)Mrph}
	Smn1^tm1Jme/Smn1^tm1Jme Tg(Eno2-cre)39Jme/0 (conditional)
	Smn1^tm1Jme/Smn1^tm1.1Jme Tg(Eno2-cre)39Jme/0 (conditional)
	Smn1^tm1Jme/Smn1^tm1.1Jme Tg(ACTA1-cre)79Jme/0 (conditional)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 04/30/2024 MGI 6.23