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Symbol
Name
ID
Dspp
dentin sialophosphoprotein
MGI:109172
Phenotype annotations related to craniofacial
Darker colors indicate more annotations
Human Phenotypes
Grayish enamel
Hypocalcification of dental enamel
Generalized hypoplasia of dental enamel
Dentinogenesis imperfecta
Dentinogenesis imperfecta limited to primary teeth
Shell teeth
Selective tooth agenesis
Persistence of primary teeth
Abnormality of dental morphology
Taurodontia
Abnormality of the dental root
Short dental roots
Microdontia
Yellow-brown discoloration of the teeth
Abnormality of dentin
Abnormality of the dental pulp
Obliteration of the pulp chamber
Pulp stones
Fragile teeth
Anterior open-bite malocclusion
Periapical bone loss
Disease(s) Associated with DSPP
dentin dysplasia
dentinogenesis imperfecta

Mouse Phenotypes
abnormal alveolar process morphology
alveolar process atrophy
abnormal tooth morphology
abnormal dental pulp cavity morphology
abnormal periodontal ligament morphology
abnormal dentin mineralization
abnormal predentin morphology
abnormal cementum morphology
abnormal dentin morphology
abnormal enamel morphology
abnormal enamel rod pattern
enamel pits
reduced enamel thickness
brittle teeth
abnormal junctional epithelium morphology
detached junctional epithelium
abnormal periodontium morphology
periodontal pocket
Availability Mouse Genotype
Dspptm1Kul/Dspptm1Kul
Tg(Amelx-Dspp)13Mlp/Tg(Amelx-Dspp)13Mlp
Tg(Amelx-Dspp)214Mlp/Tg(Amelx-Dspp)214Mlp

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
10/13/2020
MGI 6.16
The Jackson Laboratory