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Symbol
Name
ID

Lig3
ligase III, DNA, ATP-dependent
MGI:109152

Phenotype annotations related to muscle

Darker colors indicate more annotations

Human Phenotypes	Multiple mitochondrial DNA deletions
Disease(s) Associated with LIG3	Multiple mitochondrial DNA deletions
mitochondrial DNA depletion syndrome 20

Mouse Phenotypes		abnormal myocardial fiber morphology	decreased cardiac muscle contractility
Availability	Mouse Genotype
	Lig3^tm1.1Pmc/Lig3^tm1.1Pmc Tg(Ckmm-cre)5Khn/0 (conditional)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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