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Symbol
Name
ID
Nfe2l2
nuclear factor, erythroid derived 2, like 2
MGI:108420
Phenotype annotations related to homeostasis/metabolism
*Aspects of the system are reported to show a normal phenotype.
Darker colors indicate more annotations

Mouse Phenotypes
homeostasis/metabolism phenotype
increased circulating creatinine level
decreased glutathione level
decreased urine creatinine level
increased circulating bilirubin level
decreased circulating glucose level
hypoglycemia
increased circulating phosphate level
decreased circulating interleukin-1 beta level
increased circulating interleukin-1 beta level
increased circulating interleukin-6 level
increased circulating tumor necrosis factor level
increased circulating alanine transaminase level
increased circulating alkaline phosphatase level
increased circulating aspartate transaminase level
abnormal enzyme/coenzyme level
decreased catalase level
increased lactate dehydrogenase level
abnormal iron homeostasis
abnormal iron level
increased liver iron level
abnormal lipid homeostasis
increased urine protein level
abnormal enzyme/coenzyme activity
decreased glutathione peroxidase activity
abnormal physiological response to xenobiotic
increased susceptibility to xenobiotic induced morbidity/mortality
increased physiological sensitivity to xenobiotic
increased incidence of tumors by chemical induction
increased susceptibility to ischemic brain injury
increased cerebral infarct size
increased susceptibility to injury
Availability Mouse Genotype
Nfe2l2em1(IMPC)Ccpcz/Nfe2l2em1(IMPC)Ccpcz
Nfe2l2tm1Mym/Nfe2l2tm1Mym *
Nfe2l2tm1Ywk/Nfe2l2tm1Ywk *
Nfe2l2tm1Mym/Nfe2l2+
Nfe2l2tm1.1Sred/Nfe2l2tm1.1Sred
Tg(Scgb1a1-cre)1Grau/0  (conditional)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/30/2024
MGI 6.23
The Jackson Laboratory