Symbol
Name
ID

Wnt10a
wingless-type MMTV integration site family, member 10A
MGI:108071

Phenotype annotations related to integument

Darker colors indicate more annotations

Human Phenotypes

Sparse scalp hair

Aplasia/Hypoplasia of the eyebrow

Sparse eyebrow

Short eyelashes

Palmoplantar hyperhidrosis

Palmoplantar keratoderma

Palmar hyperkeratosis

Facial telangiectasia

Abnormal hair morphology

Alopecia

Sparse hair

Sparse body hair

Abnormal fingernail morphology

Dystrophic fingernails

Dystrophic toenail

Small nail

Narrow nail

Ridged nail

Nail dystrophy

Onycholysis

Thin nail

Apocrine hidrocystoma

Poroma

Anhidrosis

Hypohidrosis

Abnormal skin morphology

Dry skin

Ectodermal dysplasia

Thin skin

Hyperkeratosis

Basal cell carcinoma

Squamous cell carcinoma

Disease(s) Associated with WNT10A

Schopf-Schulz-Passarge syndrome

tooth agenesis

Mouse Phenotypes

enlarged sebaceous gland

abnormal sweat gland morphology

abnormal sebaceous lipid secretion

hypohidrosis

abnormal coat/ hair morphology

abnormal coat/hair pigmentation

abnormal nail morphology

small hair follicles

abnormal hair cycle anagen phase

accelerated hair follicle regression

abnormal hair follicle physiology

Availability

Mouse Genotype

Wnt10a^{tm1.1(KOMP)Vlcg}/Wnt10a^{tm1.1(KOMP)Vlcg}

Wnt10a^tm1.1Smr/Wnt10a^tm1.1Smr

Tg(KRT5-rtTA)#Glk/0
Tg(tetO-cre)1Jaw/0
Wnt10a^tm1Smr/Wnt10a^tm1Smr (conditional)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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