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Symbol
Name
ID
Smad2
SMAD family member 2
MGI:108051
Phenotype annotations related to embryo
Darker colors indicate more annotations

Mouse Phenotypes
abnormal developmental patterning
failure to gastrulate
abnormal proximal-distal axis patterning
abnormal rostral-caudal axis patterning
rostral body truncation
embryonic growth arrest
embryonic growth retardation
decreased embryo size
abnormal embryonic tissue morphology
abnormal anterior definitive endoderm morphology
abnormal embryonic epiblast morphology
abnormal egg cylinder morphology
absent ectoderm
absent endoderm
absent mesoderm
absent head fold
absent notochord
absent primitive node
failure of primitive streak formation
abnormal embryonic-extraembryonic boundary morphology
abnormal ectoplacental cone morphology
abnormal primitive streak elongation
abnormal extraembryonic tissue morphology
absent allantois
absent amnion
abnormal chorion morphology
absent chorion
absent extraembryonic ectoderm
abnormal proamniotic cavity morphology
abnormal extraembryonic endoderm formation
failure of chorioallantoic fusion
abnormal visceral endoderm morphology
Availability Mouse Genotype
Smad2m1Mag/Smad2m1Mag
Smad2tm1.2Mwst/Smad2tm1.2Mwst
Smad2tm1Cxd/Smad2tm1Cxd
Smad2tm1Enl/Smad2tm1Enl
Smad2tm1Kato/Smad2tm1Kato
Smad2tm1Rak/Smad2tm1Rak
Smad2tm1Rob/Smad2tm1Rob
Smad2tm2.1Rob/Smad2tm2.1Rob
Smad2tm2Enl/Smad2tm2Enl
Smad2tm2Kato/Smad2tm2Kato
Smad2m1Mag/Smad2tm1Rob
Smad2tm1.2Mwst/Smad2+
Smad2tm1Enl/Smad2+
Smad2tm1Mwst/Smad2tm1.2Mwst
Smad2tm1Rob/Smad2tm2.1Rob
Smad2tm2Enl/Smad2+
Smad2tm1Rob/Smad2tm2Rob
Edil3Tg(Sox2-cre)1Amc/Edil3+  (conditional)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/07/2024
MGI 6.23
The Jackson Laboratory