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Symbol
Name
ID
Sqstm1
sequestosome 1
MGI:107931
Phenotype annotations related to behavior/neurological
*Aspects of the system are reported to show a normal phenotype.
Darker colors indicate more annotations
Human Phenotypes
Urinary incontinence
Bone pain
Apathy
Personality changes
Disinhibition
Disease(s) Associated with SQSTM1
frontotemporal dementia and/or amyotrophic lateral sclerosis 3
neurodegeneration with ataxia, dystonia, and gaze palsy, childhood-onset
Paget's disease of bone 3

Mouse Phenotypes
behavior/neurological phenotype
abnormal behavior
increased food intake
decreased locomotor activity
Availability Mouse Genotype
Sqstm1tm1a(KOMP)Wtsi/Sqstm1tm1a(KOMP)Wtsi
Sqstm1tm1Keta/Sqstm1tm1Keta
Sqstm1tm1.1Ewa/Sqstm1tm1.1Ewa
Tg(Nes-cre)1Kag/0  (conditional)
Sqstm1tm2.1Jmos/Sqstm1tm2.1Jmos
Tg(Fabp4-cre)1Rev/0  (conditional)
*
Sqstm1tm2.1Jmos/Sqstm1tm2.1Jmos
Tg(Nes-cre)1Kln/0  (conditional)
*
Sqstm1tm2.1Jmos/Sqstm1tm2.1Jmos
Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+  (conditional)
*

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory