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Symbol
Name
ID
Tfam
transcription factor A, mitochondrial
MGI:107810
Phenotype annotations related to homeostasis/metabolism
Darker colors indicate more annotations
Human Phenotypes
Hypoalbuminemia
Hypoglycemia
Ascites
Disease(s) Associated with TFAM
mitochondrial DNA depletion syndrome 15

Mouse Phenotypes
decreased insulin secretion
abnormal circulating insulin level
decreased dopamine level
abnormal enzyme/coenzyme level
increased insulin sensitivity
increased glutathione peroxidase activity
increased physiological sensitivity to xenobiotic
Availability Mouse Genotype
Tfamtm1Lrsn/Tfamtm1Lrsn
Tg(Ckmm-cre)1Lrsn/0  (conditional)
Tfamtm1Lrsn/Tfamtm1Lrsn
Tg(Ins2-cre)25Mgn/0  (conditional)
Slc6a3tm1(cre)Lrsn/Slc6a3+
Tfamtm1Lrsn/Tfamtm1Lrsn  (conditional)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
10/01/2019
MGI 6.14
The Jackson Laboratory