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Symbol
Name
ID
Tfam
transcription factor A, mitochondrial
MGI:107810
Phenotype annotations related to growth/size/body
Darker colors indicate more annotations
Human Phenotypes
Ascites
Abdominal distention
Failure to thrive
Cachexia
Intrauterine growth retardation
Disease(s) Associated with TFAM
amyotrophic lateral sclerosis
mitochondrial DNA depletion syndrome 15

Mouse Phenotypes
increased heart weight
enlarged heart
slow postnatal weight gain
weight loss
decreased body size
postnatal growth retardation
distended abdomen
Availability Mouse Genotype
Tfamtm1.1Lrsn/Tfamtm1.1Lrsn
Tfamtm1.1Ncdl/Tfamtm1.1Ncdl
Tg(KRT14-cre)1Amc/0  (conditional)
Tfamtm1Lrsn/Tfamtm1Lrsn
Tg(Ckmm-cre)1Lrsn/0  (conditional)
Tfamtm1Lrsn/Tfamtm1Lrsn
Tg(Myhca-cre)1Lrsn/0  (conditional)
Myl1tm1(cre)Sjb/Myl1+
Tfamtm1Lrsn/Tfamtm1Lrsn  (conditional)
Cnptm1(cre)Kan/Cnp+
Tfamtm1Lrsn/Tfamtm1Lrsn  (conditional)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory