Symbol
Name
ID

Phex
phosphate regulating endopeptidase homolog, X-linked
MGI:107489

Phenotype annotations related to homeostasis/metabolism

Darker colors indicate more annotations

Human Phenotypes	Abnormal circulating calcium concentration	Hypophosphatemia	Hypophosphatemic rickets	Elevated circulating alkaline phosphatase concentration	Renal phosphate wasting	Elevated circulating parathyroid hormone level
Disease(s) Associated with PHEX
X-linked dominant hypophosphatemic rickets

Mouse Phenotypes

increased urine creatinine level

abnormal blood homeostasis

increased circulating parathyroid hormone level

decreased circulating calcium level

decreased circulating phosphate level

decreased circulating potassium level

decreased circulating C-reactive protein level

decreased circulating alkaline phosphatase level

increased circulating alkaline phosphatase level

abnormal renal glucose reabsorption

abnormal renal phosphate reabsorption

abnormal vitamin D level

decreased vitamin D level

decreased urine calcium level

abnormal urine nucleotide level

increased urine phosphate level

Availability

Mouse Genotype

Phex^Hyp/Phex^Hyp

Phex^Mhdabap012/Phex^Mhdabap012

Phex^Mhdabap024/Phex^Mhdabap024

Phex^Ska1/Phex^Ska1

Phex^Hpr/Phex⁺

Phex^Hyp/Phex⁺

Phex^Hyp/Phex⁺
Tg(Bglap2-Phex)1Ldq/?

Phex^m1Jrt/Phex⁺

Phex^Mhdabap024/Phex⁺

Phex^Ska1/Phex⁺

Phex^Hpr/Y

Phex^Hyp-2J/Y

Phex^Hyp-Duk/Y

Phex^Hyp/Y

Phex^m1Jrt/Y

Phex^Mhdabap024/Y

Phex^Pug/Y

Phex^Ska1/Y

Phex^tm1.2Mkd/Y

Phex^Hyp/?

Phex^tm1.1Mkd/Y
Tg(BGLAP-cre)1Clem/0 (conditional)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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