|
Symbol Name ID |
Il6ra
interleukin 6 receptor, alpha MGI:105304 |
| * | Aspects of the system are reported to show a normal phenotype. |
| Darker colors indicate more annotations |
| Human Phenotypes | Decreased resting energy expenditure |
Increased level of L-fucose in urine |
| Disease(s) Associated with IL6R | ||
| obesity | ||
| stomach cancer |
| Mouse Phenotypes | homeostasis/metabolism phenotype |
decreased insulin secretion |
increased insulin secretion |
decreased circulating interleukin-1 beta level |
increased circulating interleukin-6 level |
decreased circulating tumor necrosis factor level |
increased circulating tumor necrosis factor level |
increased circulating aspartate transaminase level |
abnormal circulating serum amyloid protein level |
impaired glucose tolerance |
abnormal glycogen homeostasis |
increased glycogen catabolism rate |
decreased liver glycogen level |
insulin resistance |
decreased incidence of tumors by chemical induction |
abnormal wound healing |
|
| Availability | Mouse Genotype | ||||||||||||||||
| Il6ratm1.1(IL6R)Csk/Il6ratm1.1(IL6R)Csk | |||||||||||||||||
| Il6ratm1.2Drew/Il6ratm1.2Drew | |||||||||||||||||
| Il6ratm1.2Jcbr/Il6ratm1.2Jcbr | |||||||||||||||||
| Il6ratm1.1Drew/Il6ratm1.1Drew Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+ (conditional) |
* | ||||||||||||||||
| Il6ratm1.1Jcbr/Il6ratm1.1Jcbr Tg(Alb1-cre)7Gsc/0 (conditional) |
* | ||||||||||||||||
| Il6ratm1.1Jcbr/Il6ratm1.1Jcbr Lyz2tm1(cre)Ifo/Lyz2+ (conditional) |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/16/2024 MGI 6.23 |
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