|
Symbol Name ID |
Gpx1
glutathione peroxidase 1 MGI:104887 |
| Darker colors indicate more annotations |
| Human Phenotypes | Increased circulating IgA level |
Increased circulating IgG level |
Decreased circulating antibody level |
Paraproteinemia |
Hypercalcemia |
Unconjugated hyperbilirubinemia |
Increased LDL cholesterol concentration |
Hypercholesterolemia |
Hypertriglyceridemia |
Elevated circulating creatinine concentration |
Hyperproteinemia |
Increased circulating lactate dehydrogenase concentration |
Glucose intolerance |
Diabetes mellitus |
Type II diabetes mellitus |
Impaired glucose tolerance |
Peau d'orange |
Pleural effusion |
Abnormality of vitamin B12 metabolism |
Hematuria |
Increased level of L-fucose in urine |
Amyloidosis |
Medial calcification of large arteries |
Medial calcification of medium-sized arteries |
Cerebral calcification |
Calcification of falx cerebri |
| Disease(s) Associated with GPX1 | ||||||||||||||||||||||||||
| coronary artery disease | ||||||||||||||||||||||||||
| multiple myeloma | ||||||||||||||||||||||||||
| pseudoxanthoma elasticum | ||||||||||||||||||||||||||
| sickle cell anemia | ||||||||||||||||||||||||||
| stomach cancer |
| Mouse Phenotypes | decreased myocardial infarct size |
abnormal platelet physiology |
abnormal lipid level |
abnormal enzyme/coenzyme activity |
abnormal catalase activity |
decreased glutathione peroxidase activity |
increased glutathione peroxidase activity |
abnormal response to injury |
increased susceptibility to ischemic brain injury |
increased cerebral infarct size |
|
| Availability | Mouse Genotype | ||||||||||
| Gpx1tm1Kola/Gpx1tm1Kola | |||||||||||
| Gpx1tm1Mgr/Gpx1tm1Mgr | |||||||||||
| Gpx1tm1Ysh/Gpx1tm1Ysh | |||||||||||
| Gpx1tm1Ysh/Gpx1+ | |||||||||||
| Tg(Gpx1)41Dkd/0 | |||||||||||
| Tg(Gpx1)41Spec/0 | |||||||||||
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/23/2024 MGI 6.23 |
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