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Symbol
Name
ID

Pls3
plastin 3 (T-isoform)
MGI:104807

Phenotype annotations related to skeleton

*	Aspects of the system are reported to show a normal phenotype.
	Darker colors indicate more annotations

Human Phenotypes	Prominent sternum	Osteoporosis
Disease(s) Associated with PLS3	Prominent sternum	Osteoporosis
congenital diaphragmatic hernia
osteoporosis

Mouse Phenotypes

skeleton phenotype

decreased femur compact bone thickness

decreased bone mineral density

increased bone mineral density

decreased bone volume

decreased compact bone area

decreased bone trabecula number

increased bone trabecular spacing

osteoporosis

abnormal skeleton physiology

increased bone resorption

decreased bone stiffness

decreased bone strength

Availability

Mouse Genotype

Pls3^em1Bult/Pls3^em1Bult

Pls3^em2Bult/Pls3^em2Bult

Pls3^{tm1d(EUCOMM)Wtsi}/Pls3^{tm1d(EUCOMM)Wtsi}

*

Pls3^em1Bult/Y

Pls3^em2Bult/Y

Pls3^{tm1d(EUCOMM)Wtsi}/Y

*

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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