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Symbol
Name
ID
Hand2
heart and neural crest derivatives expressed 2
MGI:103580
Phenotype annotations related to embryo
*Aspects of the system are reported to show a normal phenotype.
Darker colors indicate more annotations

Mouse Phenotypes
embryo phenotype
abnormal pharyngeal arch artery morphology
abnormal first pharyngeal arch artery morphology
absent second pharyngeal arch artery
increased embryonic tissue cell apoptosis
abnormal first pharyngeal arch morphology
absent pharyngeal arches
pharyngeal arch hypoplasia
embryonic growth retardation
decreased embryo size
abnormal apical ectodermal ridge morphology
abnormal limb bud morphology
abnormal forelimb bud morphology
small forelimb buds
decreased somite size
incomplete somite formation
Availability Mouse Genotype
Hand2tm1.2Zllr/Hand2tm1.2Zllr
Hand2tm1Dsr/Hand2tm1Dsr
Hand2tm1Majh/Hand2tm1Majh
Hand2tm2Eno/Hand2tm2Eno
Hand2tm1.1Majh/Hand2tm1.1Majh
H2az2Tg(Wnt1-cre)11Rth/H2az2+  (conditional)
Hand2tm1Cse/Hand2+
H2az2Tg(Wnt1-cre)11Rth/H2az2+  (conditional)
*
Hand2tm1Cse/Hand2+
Tg(Hoxb6-cre)#Mku/0  (conditional)
*

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/30/2024
MGI 6.23
The Jackson Laboratory