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Symbol
Name
ID
Grb10
growth factor receptor bound protein 10
MGI:103232
Phenotype annotations related to homeostasis/metabolism
*Aspects of the system are reported to show a normal phenotype.
Darker colors indicate more annotations

Mouse Phenotypes
homeostasis/metabolism phenotype
decreased fatty acid oxidation
increased insulin secretion
increased susceptibility to diet-induced obesity
impaired adaptive thermogenesis
decreased circulating glucose level
increased circulating insulin level
decreased core body temperature
decreased oxygen consumption
abnormal glucose homeostasis
impaired glucose tolerance
improved glucose tolerance
increased liver glycogen level
increased insulin sensitivity
insulin resistance
Availability Mouse Genotype
Grb10GT(XC302)Byg/Grb10GT(XC302)Byg
Grb10Gt(Betageo)1Ward/Grb10+
Grb10tm1.1Fliu/Grb10tm1.1Fliu
Tg(Pdx1-cre)6Tuv/0  (conditional)
*
Grb10tm1.1Fliu/Grb10tm1.1Fliu
Tg(Fabp4-cre)1Rev/0  (conditional)
Grb10tm1.1Fliu/Grb10tm1.1Fliu
Tg(Adipoq-cre)#Pesch/0  (conditional)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/30/2024
MGI 6.23
The Jackson Laboratory