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Symbol
Name
ID

Vhl
von Hippel-Lindau tumor suppressor
MGI:103223

Phenotype annotations related to neoplasm

*	Aspects of the system are reported to show a normal phenotype.
	Darker colors indicate more annotations

Human Phenotypes

Retinal capillary hemangioma

Breast carcinoma

Pulmonary capillary hemangiomatosis

Hemangioma

Hepatic hemangioma

Colon cancer

Neoplasm of the liver

Neoplasm of the pancreas

Pancreatic adenocarcinoma

Paraganglioma

Pheochromocytoma

Papillary cystadenoma of the epididymis

Ovarian carcinoma

Renal cell carcinoma

Cerebellar hemangioblastoma

Spinal hemangioblastoma

Neoplasm

Melanoma

Disease(s) Associated with VHL

familial erythrocytosis 2

pancreatic cancer

pheochromocytoma

renal cell carcinoma

von Hippel-Lindau disease

Mouse Phenotypes		neoplasm	increased pancreas adenoma incidence	increased incidence of tumors by chemical induction	increased hepatic hemangioma incidence	increased adenocarcinoma incidence	preneoplasia
Availability	Mouse Genotype	neoplasm	increased pancreas adenoma incidence	increased incidence of tumors by chemical induction	increased hepatic hemangioma incidence	increased adenocarcinoma incidence	preneoplasia
	Vhl^tm1Mcs/Vhl^tm1Mcs	*
	Vhl^tm1.1Jae/Vhl⁺
	Vhl^tm1.1Lss/Vhl⁺
	Vhl^tm1.1Wkr/Vhl⁺
	Vhl^tm1Lss/Vhl^tm1.1Lss
	Vhl^tm1Wml/Vhl⁺
	Hprt1^{tm1(Pck1-cre)Vhh}/Y Vhl^tm1Jae/Vhl^tm1Jae (conditional)
	Vhl^tm1Lss/Vhl^tm1Lss Tg(Pdx1-cre)89.1Dam/0 (conditional)
	Vhl^tm1Lss/Vhl^tm1.1Lss Tg(ACTB-cre)1Tes/0 (conditional)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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