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Symbol
Name
ID
Vhl
von Hippel-Lindau tumor suppressor
MGI:103223
Phenotype annotations related to growth/size/body
Darker colors indicate more annotations
Human Phenotypes
Hepatosplenomegaly
Peritoneal abscess
Failure to thrive
Weight loss
Disease(s) Associated with VHL
familial erythrocytosis 2
pancreatic cancer

Mouse Phenotypes
increased heart weight
embryonic growth retardation
decreased embryo size
pancreas cyst
decreased body weight
cachexia
kidney cyst
kidney cortex cyst
decreased body size
enlarged liver
increased liver weight
enlarged spleen
increased spleen weight
Availability Mouse Genotype
Vhltm1Bjg/Vhltm1Bjg
Vhltm1Mcs/Vhltm1Mcs
Vhltm1.1Wkr/Vhl+
Vhltm1Jae/Vhltm1Jae
Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+  (conditional)
Hprt1tm1(Pck1-cre)Vhh/Y
Vhltm1Jae/Vhltm1Jae  (conditional)
Vhltm1Jae/Vhltm1Jae
Tg(KRT14-cre)1Ipc/0  (conditional)
Vhltm1Jae/Vhltm1Jae
Tg(Myh6-cre)2182Mds/0  (conditional)
Vhltm1Jae/Vhltm1Jae
Tg(Sp7-tTA,tetO-EGFP/cre)1Amc/0  (conditional)
Vhltm1Jae/Vhltm1Jae
Tg(NPHS2-cre)295Lbh/?  (conditional)
Vhltm1Lss/Vhltm1Lss
Tg(Pdx1-cre)89.1Dam/0  (conditional)
Vhltm1Lss/Vhltm1.1Lss
Tg(CAG-cre/Esr1*)1Lbe/0  (conditional)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory