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Symbol Name ID |
Stat3
signal transducer and activator of transcription 3 MGI:103038 |
| Darker colors indicate more annotations |
| Human Phenotypes | Increased circulating IgE level |
| Disease(s) Associated with STAT3 | |
| hyper IgE recurrent infection syndrome 1 |
| Mouse Phenotypes | increased cardiomyocyte apoptosis |
increased thymocyte apoptosis |
increased T cell apoptosis |
increased apoptosis |
pulmonary epithelial necrosis |
decreased keratinocyte migration |
decreased T cell proliferation |
decreased inner cell mass proliferation |
increased keratinocyte proliferation |
decreased hepatocyte proliferation |
oxidative stress |
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| Availability | Mouse Genotype | |||||||||||
| Stat3tm1Aki/Stat3tm1Aki | ||||||||||||
| Stat3tm1Dnl/Stat3tm1Dlv | ||||||||||||
| Tg(KRT5-Stat3*A661C*N663C)1Jdg/0 | ||||||||||||
| Stat3tm1Vpo/Stat3tm1Vpo Tg(Myh6-cre)2182Mds/0 (conditional) |
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| Stat3tm2Aki/Stat3tm2Aki Tg(Lck-cre)1Jtak/0 (conditional) |
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| Stat3tm2Aki/Stat3tm2Aki Tg(KRT5-cre/ERT2)AJdg/0 (conditional) |
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| Stat3tm2Aki/Stat3tm2Aki Tg(SFTPC-rtTA)5Jaw/0 Tg(tetO-cre)1Jaw/0 (conditional) |
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| Stat3tm2Aki/Stat3tm2Aki Tg(KRT5-cre)1Tak/0 (conditional) |
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| Stat3tm1Xyfu/Stat3tm1.1Xyfu Tg(Ttr-cre)10-3Xyfu/? (conditional) |
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| Stat3tm1Xyfu/Stat3tm1.1Xyfu Tg(Myh6-cre)2182Mds/0 (conditional) |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/23/2024 MGI 6.23 |
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