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Symbol
Name
ID

Cacna1c
calcium channel, voltage-dependent, L type, alpha 1C subunit
MGI:103013

Phenotype annotations related to mortality/aging

Darker colors indicate more annotations

Human Phenotypes	Sudden cardiac death	Sudden death
Disease(s) Associated with CACNA1C	Sudden cardiac death	Sudden death
Brugada syndrome 3
Timothy syndrome

Mouse Phenotypes		premature death	lethality throughout fetal growth and development, complete penetrance	lethality throughout fetal growth and development, incomplete penetrance	neonatal lethality, complete penetrance	postnatal lethality, complete penetrance	prenatal lethality prior to heart atrial septation	preweaning lethality, complete penetrance
Availability	Mouse Genotype	premature death			neonatal lethality, complete penetrance	postnatal lethality, complete penetrance	prenatal lethality prior to heart atrial septation	preweaning lethality, complete penetrance
	Cacna1c^em1(IMPC)Mbp/Cacna1c^em1(IMPC)Mbp
	Cacna1c^tm1Dgen/Cacna1c^tm1Dgen
	Cacna1c^tm1Hfm/Cacna1c^tm1Hfm
	Cacna1c^tm1Itl/Cacna1c^tm1Itl
	Cacna1c^tm2Hfm/Cacna1c^tm2Hfm
	Cacna1c^tm2Itl/Cacna1c^tm2Itl
	Cacna1c^tm5.1Hfm/Cacna1c^tm5.1Hfm
	Cacna1c^tm2Itl/Cacna1c⁺
	Cacna1c^tm1Ggm/Cacna1c^tm1Ggm A1cf^{Tg(Myh6-cre/Esr1*)1Jmk}/A1cf⁺ (conditional)
	Cacna1c^tm3Hfm/Cacna1c^tm4Hfm A1cf^{Tg(Myh6-cre/Esr1*)1Jmk}/A1cf⁺ (conditional)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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