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Symbol Name ID |
Cacna1c
calcium channel, voltage-dependent, L type, alpha 1C subunit MGI:103013 |
| * | Aspects of the system are reported to show a normal phenotype. |
| Darker colors indicate more annotations |
| Human Phenotypes | Autism |
| Disease(s) Associated with CACNA1C | |
| Timothy syndrome |
| Mouse Phenotypes | behavior/neurological phenotype |
abnormal learning/memory/conditioning |
enhanced contextual conditioning behavior |
enhanced cued conditioning behavior |
decreased exploration in new environment |
abnormal long-term spatial reference memory |
behavioral despair |
increased thigmotaxis |
increased freezing behavior |
excessive scratching |
abnormal motor capabilities/coordination/movement |
impaired coordination |
decreased locomotor activity |
increased stereotypic behavior |
increased chemical nociceptive threshold |
abnormal social investigation |
decreased vocalization |
decreased aerobic running capacity |
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| Availability | Mouse Genotype | ||||||||||||||||||
| Cacna1ctm1.1Wac/Cacna1ctm1.1Wac | |||||||||||||||||||
| Cacna1ctm1Jst/Cacna1ctm1Jst | |||||||||||||||||||
| Cacna1ctm2.1Wac/Cacna1ctm2.1Wac | |||||||||||||||||||
| Cacna1cem1(IMPC)Mbp/Cacna1c+ | |||||||||||||||||||
| Cacna1ctm1Dgen/Cacna1c+ | |||||||||||||||||||
| Cacna1ctm2Itl/Cacna1c+ | * | ||||||||||||||||||
| Cacna1ctm1.1Knt/Cacna1ctm1.1Knt (conditional) | * | ||||||||||||||||||
| Cacna1ctm1Ggm/Cacna1ctm1Ggm Tg(Camk2a-cre)1557Sva/0 (conditional) |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/30/2024 MGI 6.23 |
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