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Symbol
Name
ID
Six3
sine oculis-related homeobox 3
MGI:102764
Phenotype annotations related to skeleton
Darker colors indicate more annotations
Human Phenotypes
Abnormal skull morphology
Frontal bossing
Flat occiput
Aplasia of the premaxilla
Hypoplasia of the zygomatic bone
Malar flattening
Dandy-Walker malformation
Microcephaly
Macrocephaly
Encephalocele
Absent nasal septal cartilage
Aplasia of the nasal bone
Short neck
Hand polydactyly
Brachydactyly
Joint hypermobility
Scoliosis
Abnormal form of the vertebral bodies
Disease(s) Associated with SIX3
holoprosencephaly
holoprosencephaly 2

Mouse Phenotypes
abnormal cranium morphology
Availability Mouse Genotype
Six3tm1Gco/Six3tm1Gco

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory