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Symbol Name ID |
Runx3
runt related transcription factor 3 MGI:102672 |
| * | Aspects of the system are reported to show a normal phenotype. |
| Darker colors indicate more annotations |
| Human Phenotypes | Back pain |
| Disease(s) Associated with RUNX3 | |
| pancreatic cancer |
| Mouse Phenotypes | skeleton phenotype |
decreased osteoblast proliferation |
abnormal cranium morphology |
small neurocranium |
short humerus |
decreased diameter of femur |
decreased femoral compact bone area |
short femur |
abnormal skeleton morphology |
abnormal clavicle morphology |
decreased length of long bones |
kyphosis |
lordosis |
scoliosis |
decreased bone mineral content |
decreased bone mineral density of femur |
decreased bone mineral density |
decreased trabecular bone volume |
decreased bone volume |
decreased compact bone area |
decreased compact bone thickness |
decreased osteoblast cell number |
abnormal trabecular bone morphology |
decreased trabecular bone thickness |
decreased bone mass |
abnormal skeleton development |
abnormal bone mineralization |
abnormal intramembranous bone ossification |
delayed bone ossification |
decreased bone stiffness |
decreased bone strength |
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| Availability | Mouse Genotype | |||||||||||||||||||||||||||||||
| Runx3tm1Yg/Runx3tm1Yg | * | |||||||||||||||||||||||||||||||
| Runx3tm3.1Yg/Runx3tm3.1Yg | ||||||||||||||||||||||||||||||||
| Runx3tm3Yg/Runx3tm3Yg Tg(Col1a1-cre)1Kry/0 (conditional) |
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| Runx3tm3Yg/Runx3tm3Yg Tg(Col2a1-cre)1Bhr/0 (conditional) |
* | |||||||||||||||||||||||||||||||
| Runx3tm3Yg/Runx3tm3Yg Tg(Scx-GFP)1Stzr/0 (conditional) |
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| Runx3tm3Yg/Runx3tm3Yg H2az2Tg(Wnt1-cre)11Rth/H2az2+ (conditional) |
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| Runx3tm3Yg/Runx3tm3Yg Tg(Pou4f1-cre/ERT2)2Jiz/0 (conditional) |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/16/2024 MGI 6.23 |
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