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Symbol Name ID |
Pou3f4
POU domain, class 3, transcription factor 4 MGI:101894 |
| * | Aspects of the system are reported to show a normal phenotype. |
| Darker colors indicate more annotations |
| Human Phenotypes | Dilatated internal auditory canal |
Stapes ankylosis |
Conductive hearing impairment |
Mixed hearing impairment |
Congenital sensorineural hearing impairment |
Progressive sensorineural hearing impairment |
| Disease(s) Associated with POU3F4 | ||||||
| X-linked deafness 2 |
| Mouse Phenotypes | hearing/vestibular/ear phenotype |
abnormal internal auditory canal morphology |
abnormal bony labyrinth |
abnormal oval window morphology |
abnormal stapes morphology |
abnormal stapes crus morpholgy |
abnormal stapes footplate morphology |
abnormal cochlea morphology |
abnormal Reissner membrane morphology |
detached Reissner membrane |
distended Reissner membrane |
cochlear outer hair cell degeneration |
abnormal spiral ligament fibrocyte morphology |
abnormal type I spiral ligament fibrocytes |
abnormal type II spiral ligament fibrocytes |
abnormal stria vascularis morphology |
abnormal scala tympani morphology |
small scala tympani |
abnormal spiral limbus morphology |
decreased cochlea coiling |
abnormal lateral semicircular canal morphology |
abnormal superior semicircular canal morphology |
dilated endolymphatic duct |
decreased endocochlear potential |
increased or absent threshold for auditory brainstem response |
impaired hearing |
conductive hearing loss |
deafness |
sensorineural hearing loss |
abnormal vestibular system physiology |
|
| Availability | Mouse Genotype | ||||||||||||||||||||||||||||||
| Pou3f4sdl/Pou3f4sdl | * | ||||||||||||||||||||||||||||||
| Pou3f4Slf/Pou3f4Slf | |||||||||||||||||||||||||||||||
| Pou3f4tm1Tno/Pou3f4tm1Tno | |||||||||||||||||||||||||||||||
| Pou3f4tm1Tno/Pou3f4+ | |||||||||||||||||||||||||||||||
| Pou3f4sdl/Y | |||||||||||||||||||||||||||||||
| Pou3f4Slf/Y | |||||||||||||||||||||||||||||||
| Pou3f4tm1Cren/Y | |||||||||||||||||||||||||||||||
| Pou3f4tm1Tno/Y | |||||||||||||||||||||||||||||||
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/16/2024 MGI 6.23 |
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