Symbol
Name
ID

Cd79a
CD79A antigen (immunoglobulin-associated alpha)
MGI:101774

Phenotype annotations related to immune system

*	Aspects of the system are reported to show a normal phenotype.
	Darker colors indicate more annotations

Human Phenotypes	Agammaglobulinemia	Absent isohemagglutinin level	Neutropenia	Absent circulating B cells	Abnormal T cell morphology	Recurrent otitis media	Recurrent bacterial infections	Recurrent lower respiratory tract infections	Recurrent bronchitis
Disease(s) Associated with CD79A
agammaglobulinemia 3

Mouse Phenotypes

immune system phenotype

decreased B cell proliferation

abnormal B cell differentiation

abnormal class switch recombination

decreased immature B cell number

absent immature B cells

increased immature B cell number

increased transitional stage B cell number

increased transitional stage T1 B cell number

increased transitional stage T2 B cell number

increased transitional stage T3 B cell number

increased pro-B cell number

arrested B cell differentiation

abnormal T cell differentiation

decreased double-positive T cell number

abnormal B cell number

decreased mature B cell number

absent mature B cells

decreased B-1 B cell number

decreased B-1a cell number

decreased follicular B cell number

decreased marginal zone B cell number

decreased B cell number

decreased pre-B cell number

absent pre-B cells

increased pre-B cell number

decreased T cell number

abnormal B cell morphology

abnormal metallophilic macrophage morphology

abnormal spleen marginal zone macrophage morphology

abnormal spleen red pulp morphology

abnormal B cell physiology

abnormal B cell activation

abnormal immunoglobulin level

decreased IgD level

decreased IgG1 level

decreased IgG2a level

decreased IgG2b level

increased IgG2b level

decreased IgG2c level

increased IgG2c level

decreased IgG3 level

decreased IgG level

decreased IgM level

decreased immunoglobulin level

abnormal immune system cell morphology

abnormal immune system physiology

abnormal humoral immune response

impaired humoral immune response

increased anti-single stranded DNA antibody level

Availability

Mouse Genotype

Cd79a^m1Anu/Cd79a^m1Anu

Cd79a^m1Btlr/Cd79a^m1Btlr

Cd79a^m2Btlr/Cd79a^m2Btlr

Cd79a^{tm1.1(BAP31N-EGFP)Pld}/Cd79a^{tm1.1(BAP31N-EGFP)Pld}

Cd79a^tm1.1Cgn/Cd79a^tm1.1Cgn

Cd79a^tm1.1Rsky/Cd79a^tm1.1Rsky

Cd79a^tm2Cgn/Cd79a^tm2Cgn

Cd79a^tm2Pld/Cd79a^tm2Pld

Cd79a^tm4.1Cgn/Cd79a^tm4.1Cgn

Cd79a^tm5.1Cgn/Cd79a^tm5.1Cgn

Cd79a^tm6Cgn/Cd79a^tm6Cgn

Cd79a^tm7Cgn/Cd79a^tm7Cgn

Cd79a^tm3Cgn/Cd79a^tm4.1Cgn

Cd79a^tm3Cgn/Cd79a^tm3Cgn
Tg(Mx1-cre)1Cgn/? (conditional)

Cd79a^tm4Cgn/Cd79a^tm4.1Cgn
Tg(Mx1-cre)1Cgn/0 (conditional)

Cd79a^tm4Cgn/Cd79a^tm4.1Cgn
Tg(Cr2-cre)3Cgn/0 (conditional)

Cd79a^tm5Cgn/Cd79a^tm5.1Cgn
Tg(Mx1-cre)1Cgn/0 (conditional)

Cd79a^tm5Cgn/Cd79a^tm5.1Cgn
Tg(Cr2-cre)3Cgn/0 (conditional)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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