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Symbol
Name
ID
Bub1
BUB1, mitotic checkpoint serine/threonine kinase
MGI:1100510
Phenotype annotations related to reproductive system
Darker colors indicate more annotations
Human Phenotypes
Uterine leiomyosarcoma
Disease(s) Associated with BUB1
colorectal cancer

Mouse Phenotypes
oligozoospermia
small seminiferous tubules
decreased testis weight
small testis
abnormal spermatogenesis
decreased litter size
male infertility
reduced male fertility
Availability Mouse Genotype
Bub1tm3.1Jvd/Bub1tm3.1Jvd
Bub1tm1Ssta/Bub1tm1Ssta
Tg(CAG-cre/Esr1*)5Amc/?  (conditional)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/31/2026
MGI 6.24
The Jackson Laboratory