About   Help   FAQ
Phenotypes associated with Efnb1tm1.1Sor/Y
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
ot1
Efnb1tm1.1Sor/Y involves: 129S4/SvJaeSor MGI:3850144

Comparison Matrix Gene Expression + Phenotype


Genotype
MGI:3850144
ot1
Allelic
Composition
Efnb1tm1.1Sor/Y
Genetic
Background
involves: 129S4/SvJaeSor
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Efnb1tm1.1Sor mutation (0 available); any Efnb1 mutation (15 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
skeleton
• mice are often born with rib pairing defects

nervous system
• the corpus callosum tract axons project ventrally along the ipsilateral septum unlike in wild-type mice
• Background Sensitivity: all mice lack a corpus callosum unlike when mice are on a mixed 129S4 background where corpus callosum formation is normal
• some mice exhibit ventral-temporal (VT) retinal ganglion cell axon mapping defects compared with control mice

hearing/vestibular/ear

craniofacial
• mice are often born with a cleft secondary palate

digestive/alimentary system
• mice are often born with a cleft secondary palate

growth/size/body
• mice are often born with a cleft secondary palate



Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
08/05/2025
MGI 6.24
The Jackson Laboratory