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Phenotypes associated with Ifi27l2atm1(KOMP)Vlcg/Ifi27l2atm1(KOMP)Vlcg
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Ifi27l2atm1(KOMP)Vlcg/Ifi27l2atm1(KOMP)Vlcg involves: C57BL/6NTac MGI:5749825

Comparison Matrix Gene Expression + Phenotype


Genotype
MGI:5749825
hm1
Allelic
Composition		 Ifi27l2atm1(KOMP)Vlcg/Ifi27l2atm1(KOMP)Vlcg
Genetic
Background		 involves: C57BL/6NTac
Cell Lines 10949A-H8
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ifi27l2atm1(KOMP)Vlcg mutation (1 available); any Ifi27l2a mutation (9 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
immune system phenotype ( J:221531 )
N
• body weight and survival rates unaffected after infection with influenza A (H1N1 and H7N7)
• viral loads in lungs are unaffected by infection with influenza A

respiratory system
abnormal bronchiole epithelium morphology ( J:221531 )
• sloughing of dead epithelial cells persists somewhat longer after infection with influenza A than observed in infected controls


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/18/2025
MGI 6.24 		The Jackson Laboratory