About   Help   FAQ
Disease Ontology Browser
progressive multifocal leukoencephalopathy (DOID:643)
Alliance: disease page
Synonyms: PML
Alt IDs: ICD10CM:A81.2, ICD9CM:046.3, MESH:D007968, NCI:C26815, UMLS_CUI:C0023524
Definition: A viral infectious disease that involves reactivation of JC polyomavirus in immune-compromised individuals which causes the loss of white matter (which is made up of myelin, a substance the surrounds and protects nerve fibers) in multiple areas of the brain. The symptoms include hemiparesis, aphasia, dysarthria, hemianopia, cognitive impairment and coma.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
MGI 6.21
The Jackson Laboratory