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Disease Ontology Browser
granulomatosis with polyangiitis (DOID:12132)
Alliance: disease page
Synonyms: Necrotizing respiratory granulomatosis; Wegener granulomatosis, formerly
Alt IDs: OMIM:608710, ICD10CM:M31.3, ICD9CM:446.4, MESH:D014890, NCI:C3444, UMLS_CUI:C3495801
Definition: An autoimmune hypersensitivity disease that is characterized by necrotizing granulomatous inflammation of the upper and lower respiratory tract, glomerulonephritis, vasculitis, and the presence of antineutrophil cytoplasmatic autoantibodies (ANCAs) in patient sera, and is located_in lung, located_in kidney, located_in skin resulting from an autoimmune attack by antineutrophil cytoplasmic antibodies against small and medium-size blood vessels.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
07/29/2020
MGI 6.15
The Jackson Laboratory