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Disease Ontology Browser
common variable immunodeficiency (DOID:12177)
Synonyms: acquired agammaglobulinemia; acquired hypogammaglobulinemia; common variable agammaglobulinemia; CVID; sporadic hypogammaglobulinemia
Alt IDs: OMIM:240500, OMIM:607594, OMIM:613493, OMIM:613494, OMIM:613495, OMIM:613496, OMIM:614699, OMIM:614700, OMIM:615577, OMIM:615767, ICD10CM:D83, ICD10CM:D83.9, ICD9CM:279.06, MESH:D017074, ORDO:1572, UMLS_CUI:C0009447
Definition: A hypogammaglobulinemia that is results in insufficient production of antibodies needed to respond to exposure of pathogens and is characterized by low Ig levels with phenotypically normal B cells that can proliferate but do not develop into Ig-producing cells. Patients with common variable immunodeficiency have marked reduction in serum levels of both immunoglobulin G (IgG) and immunoglobulin A (IgA); about half of these patients also have reduced immunoglobulin M (IgM).

Disease References using Mouse Models (3)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
05/16/2017
MGI 6.09
The Jackson Laboratory