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Disease Ontology Browser
Lynch syndrome (DOID:3883)
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Synonyms: COCA 1; Hereditary Defective Mismatch Repair syndrome; hereditary non-polyposis colon cancer type 1; hereditary nonpolyposis colorectal cancer; hereditary nonpolyposis colorectal neoplasm; HNPCC - hereditary nonpolyposis colon cancer
Alt IDs: OMIM:120435, OMIM:609310, OMIM:613244, OMIM:614331, OMIM:614337, OMIM:614350, OMIM:614385, DOID:0050586, DOID:3040, MESH:D003123, NCI:C120083, NCI:C8494, ORDO:144, UMLS_CUI:C0009405, UMLS_CUI:C1333990
Definition: An autosomal dominant disease that is characterized by an increased risk for colon cancer and cancers of the endometrium, ovary, stomach, small intestine, hepatobiliary tract, urinary tract, brain, and skin and has_material_basis_in mutation of mismatch repair genes that increases the risk of many types of cancers.

Disease References using Mouse Models (4)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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MGI 6.12
The Jackson Laboratory