type II complement component 8 deficiency (DOID:0060302)
Alliance: disease page
Alt IDs: OMIM:613789, ICD10CM:D84.1, ORDO:169150
Definition: A complement deficiency that is characterized by deficiency of the beta subunit of complement protein 8, which causes increased susceptibility to recurrent bacterial infections, especially to Neisseria meningitidis, and has_material_basis_in autosomal recessive inheritance of mutation in the C8B gene, which produces the beta subunit of complement component 8 important in forming membrane attack complexes.