multiple endocrine neoplasia type 4 (DOID:0080137)
Alliance: disease page
Synonyms: Multiple Endocrine Neoplasia, Type IV
Alt IDs: OMIM:610755, MESH:C567059
Definition: A multiple endocrine neoplasia that is characterized by hyperparathyroidism and multiple endocrine tumors and that has_material_basis_in mutations in the CDKN1B gene on chromosome 12p13 resulting in a reduction in the amount of functional p27 tumor suppressor protein which allows cells to grow and divide unchecked.