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Human Disease and Mouse Model Detail
Human Disease Cerebral Amyloid Angiopathy, App-Related
OMIM ID: 605714
Synonyms Amyloidosis, Cerebroarterial, App-Related; Amyloidosis, Hereditary, with Cerebral Hemorrhage, Dutch Variant; HCHWAD; Cerebral Amyloid Angiopathy; Cerebral Amyloid Angiopathy, App-Related, Arctic Variant; Cerebral Amyloid Angiopathy, App-Related, Dutch Variant; Cerebral Amyloid Angiopathy, App-Related, Flemish Variant; Cerebral Amyloid Angiopathy, App-Related, Iowa Variant; Cerebral Amyloid Angiopathy, App-Related, Italian Variant
View all models View ALL (10) mouse models for this human disease.
Genes and
mouse models
Mutations in human and/or mouse homologs are associated with this disease

      *Gene is associated with the disease in this species
      Mouse Homologs Human Homologs Mouse Models Mouse : Human
Homology Class
     Lrp1* LRP1 View 1 model 1:1 Homology
     App APP*   1:1 Homology
Transgenes and
other genome features
Transgenes and other genome features developed in mice to model this disease.

     Transgenes and Other Genome Features Mouse Models
  Tg(APP695)3Dbo View 1 model
  Tg(Prnp-APPSweArc)#Rmni View 1 model
  Tg(PSEN1)5Dbo View 1 model
  Tg(Thy1-APP)3Somm View 1 model
  Tg(Thy1-AppDutch)#Jckr View 4 models
  Tg(Thy1-APPSwDutIowa)BWevn View 1 model
  Tg(Thy1-APPSwe,Prnp-PSEN2*N141I)152HLaoz View 2 models
References Disease References using Mouse Models (11)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
09/16/2014
MGI 5.19
The Jackson Laboratory