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Human Disease and Mouse Model Detail
Human Disease Leber Optic Atrophy
OMIM ID: 535000
Human Phenotype Ontology associations
Synonyms Leber Hereditary Optic Neuropathy; LHON
View all models View ALL (2) mouse models for this human disease.
Genes and
mouse models
Mutations in human and/or mouse homologs are associated with this disease

      *Disease is associated/modeled with this Gene or a homolog. More...
      Human Homologs Mouse Homologs Mouse Models Homology Source
     ND6* mt-Nd6* View 1 model HomoloGene and HGNC
     ATP6* mt-Atp6   HomoloGene and HGNC
COX3* mt-Co3   HomoloGene and HGNC
CYTB* mt-Cytb   HomoloGene and HGNC
ND1* mt-Nd1   HomoloGene and HGNC
ND2* mt-Nd2   HomoloGene and HGNC
ND4* mt-Nd4   HomoloGene and HGNC
ND4L* mt-Nd4l   HomoloGene and HGNC
ND5* mt-Nd5   HomoloGene and HGNC
Transgenes and
other genome features
Transgenes and other genome features developed in mice to model this disease.

     Transgenes and Other Genome Features Mouse Models
  Tg(LONP1-mt-ND4*,-mCherry*)#Jguy View 1 model
References Disease References using Mouse Models (2)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.07
The Jackson Laboratory