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Disease Ontology Browser
acute leukemia (DOID:12603)
Synonyms: Stem cell leukaemia; Stem cell Leukemia
Alt IDs: OMIM:308960, DOID:12621, ICD10CM:C95.0, ICD10CM:C95.00, ICD9CM:208.0, NCI:C9298, NCI:C9300, UMLS_CUI:C0085669, UMLS_CUI:C1378511
Definition: A leukemia that occurs when a hematopoietic stem cell undergoes malignant transformation into a primitive, undifferentiated cell with abnormal longevity. These lymphocytes (acute lymphocytic leukemia [ALL]) or myeloid cells (acute myelocytic leukemia [AML]) proliferate abnormally, replacing normal marrow tissue and hematopoietic cells and inducing anemia, thrombocytopenia, and granulocytopenia.

Disease References using Mouse Models (3)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
08/08/2017
MGI 6.10
The Jackson Laboratory