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Human Disease and Mouse Model Detail
Human Disease Leukodystrophy, Demyelinating, Adult-Onset, Autosomal Dominant; ADLD
OMIM ID: 169500
Synonyms Pelizaeus-Merzbacher Disease, Autosomal Dominant or Late-Onset Type, Formerly
View all models View ALL (2) mouse models for this human disease.
Genes and
mouse models
Mutations in human and/or mouse homologs are associated with this disease

      *Gene is associated with the disease in this species
      Mouse Homologs Human Homologs Mouse Models Mouse : Human
Homology Class
     Lmnb1 LMNB1*   1:1 Homology
Transgenes and
other genome features
Transgenes and other genome features developed in mice to model this disease.

     Transgenes and Other Genome Features Mouse Models
  Tg(Lmnb1)1Yfu View 1 model
  Tg(Plp1-Lmnb1)#Yfu View 1 model
References Disease References using Mouse Models (1)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
10/08/2014
MGI 5.20
The Jackson Laboratory