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Human Disease and Mouse Model Detail
Human Disease Colorectal Cancer; CRC
OMIM ID: 114500
Human Phenotype Ontology associations
Synonyms Colon Cancer; Colorectal Cancer
View all models View ALL (12) mouse models for this human disease.
Genes and
mouse models
Mutations in human and/or mouse homologs are associated with this disease

      *Disease is associated/modeled with this Gene or a homolog. More...
      Human Homologs Mouse Homologs Mouse Models Homology Source
     APC* Apc* View 9 models HomoloGene and HGNC
     AKT1* Akt1   HomoloGene and HGNC
BUB1B* Bub1b   HomoloGene and HGNC
CTNNB1* Ctnnb1   HomoloGene and HGNC
DCC* Dcc   HomoloGene and HGNC
DLC1* Dlc1   HomoloGene and HGNC
EP300* Ep300   HomoloGene and HGNC
FGFR3* Fgfr3   HomoloGene and HGNC
FLCN* Flcn   HomoloGene and HGNC
NRAS* Nras   HomoloGene and HGNC
PIK3CA* Pik3ca   HomoloGene and HGNC
SRC* Src   HomoloGene and HGNC
TP53* Trp53   HomoloGene and HGNC
Transgenes and
other genome features
Transgenes and other genome features developed in mice to model this disease.

     Transgenes and Other Genome Features Mouse Models
  Tg(tetO-MYC)36aBop View 1 model
References Disease References using Mouse Models (41)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.07
The Jackson Laboratory