Gene Expression Data
Assay Details
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Assay
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Reference:
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J:242313
Forge A, et al., Disruption of SorCS2 reveals differences in the regulation of stereociliary bundle formation between hair cell types in the inner ear. PLoS Genet. 2017 Mar;13(3):e1006692
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Assay type:
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Immunohistochemistry
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MGI Accession ID:
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MGI:6414808
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Gene symbol:
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Sorcs2
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Gene name:
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sortilin-related VPS10 domain containing receptor 2
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Results
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Specimen
2A:
embryonic day 15.0-15.5
(more  )
Note: Double labeled: green - Sorcs2; red - actin
Specimen
2A:
(close  )
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Genetic Background:
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Not Specified
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Age:
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embryonic day 15.0-15.5
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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whole mount
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Fixation:
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Paraformaldehyde
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Note:
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Double labeled: green - Sorcs2; red - actin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS23: cochlea |
Absent |
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2A
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No expression is seen in the cochlear basal turn.
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Specimen
2B:
embryonic day 18.0
(more )
Note: Double labeled: green - Sorcs2; red - actin
Specimen
2B:
(close )
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Genetic Background:
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Not Specified
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Age:
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embryonic day 18.0
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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whole mount
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Fixation:
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Paraformaldehyde
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Note:
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Double labeled: green - Sorcs2; red - actin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS26: cochlea epithelium |
Present |
Regionally restricted |
2B
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Expression is localized to inner and outer hair cells in the basal turn.
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Specimen
2C:
embryonic day 18.0
(more )
Note: Double labeled: green - Sorcs2; red - actin
Specimen
2C:
(close )
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Genetic Background:
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Not Specified
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Age:
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embryonic day 18.0
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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whole mount
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Fixation:
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Paraformaldehyde
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Note:
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Double labeled: green - Sorcs2; red - actin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS26: cochlea epithelium |
Present |
Regionally restricted |
2C
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Expression is localized to inner hair cells in the apical turn.
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Specimen
2D:
embryonic day 18.0
(more )
Note: Double labeled: green - Sorcs2; red - actin
Specimen
2D:
(close )
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Genetic Background:
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Not Specified
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Age:
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embryonic day 18.0
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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whole mount
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Fixation:
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Paraformaldehyde
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Note:
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Double labeled: green - Sorcs2; red - actin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS26: macula of utricle |
Present |
Regionally restricted |
2D
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Expression is localized to presumptive immature hair cells lacking stereociliary bundles and in hair cells with bundles.
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Specimen
2E:
embryonic day 18.0
(more )
Note: Double labeled: green - Sorcs2; red - actin
Specimen
2E:
(close )
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Genetic Background:
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Not Specified
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Age:
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embryonic day 18.0
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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whole mount
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Fixation:
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Paraformaldehyde
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Note:
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Double labeled: green - Sorcs2; red - actin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS26: macula of utricle |
Present |
Regionally restricted |
2E
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Expression is localized to presumptive immature hair cells lacking stereociliary bundles and in hair cells with bundles.
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Specimen
2F:
embryonic day 18.0
(more )
Note: Double labeled: green - Sorcs2; red - actin
Specimen
2F:
(close )
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Genetic Background:
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Not Specified
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Age:
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embryonic day 18.0
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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whole mount
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Fixation:
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Paraformaldehyde
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Note:
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Double labeled: green - Sorcs2; red - actin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS26: crista ampullaris |
Present |
Regionally restricted |
2F
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Expression is localized to presumptive immature hair cells lacking stereociliary bundles and in hair cells with bundles.
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Specimen
2G:
postnatal day 0
(more )
Note: Littermate control; mouse might carry the Cre transgene. Double labeled: green - Sorcs2; red - actin.
Specimen
2G:
(close )
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Genetic Background:
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involves: C57BL/6
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Age:
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postnatal day 0
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Sex:
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Not Specified
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Type:
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whole mount
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Fixation:
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Paraformaldehyde
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Note:
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Littermate control; mouse might carry the Cre transgene. Double labeled: green - Sorcs2; red - actin.
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| Structure |
Level |
Pattern |
Image |
Note |
| TS27: organ of Corti |
Present |
Regionally restricted |
2G
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Expression is localised to hair cells and supporting cells.
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Specimen
2H:
(close )
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Genetic Background:
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involves: C57BL/6 * SJL
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Mutant Allele(s):
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Tg(Tek-cre)1Ywa/Tg(Tek-cre)1Ywa
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Age:
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postnatal day 0
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Sex:
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Not Specified
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Type:
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whole mount
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Fixation:
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Paraformaldehyde
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Note:
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Double labeled: green - Sorcs2; red - actin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS27: organ of Corti |
Absent |
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2H
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No expression is seen in hair cells and supporting cells.
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Specimen
S2C:
postnatal day 1
(more )
Note: Littermate control; mouse might carry the Cre transgene.
Specimen
S2C:
(close )
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Genetic Background:
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involves: C57BL/6
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Age:
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postnatal day 1
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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Paraformaldehyde
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Embedding:
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Gelatin
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Note:
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Littermate control; mouse might carry the Cre transgene.
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| Structure |
Level |
Pattern |
Image |
Note |
| TS27: cochlea epithelium |
Present |
Regionally restricted |
S2C
,
S2C'
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Expression is localized to hair cells and supporting cells in the basal turn.
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Specimen
S2D:
postnatal day 1
(more )
Note: Littermate control; mouse might carry the Cre transgene.
Specimen
S2D:
(close )
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Genetic Background:
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involves: C57BL/6
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Age:
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postnatal day 1
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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Paraformaldehyde
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Embedding:
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Gelatin
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Note:
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Littermate control; mouse might carry the Cre transgene.
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| Structure |
Level |
Pattern |
Image |
Note |
| TS27: cochlea epithelium |
Present |
Regionally restricted |
S2D
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S2D'
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Expression is localized to hair cells and supporting cells in the apical turn.
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Specimen
S2E:
(close )
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Genetic Background:
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involves: C57BL/6 * SJL
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Mutant Allele(s):
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Tg(Tek-cre)1Ywa/Tg(Tek-cre)1Ywa
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Age:
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postnatal day 1
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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Paraformaldehyde
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Embedding:
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Gelatin
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Specimen
S2F:
(close )
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Genetic Background:
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involves: C57BL/6 * SJL
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Mutant Allele(s):
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Tg(Tek-cre)1Ywa/Tg(Tek-cre)1Ywa
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Age:
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postnatal day 1
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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Paraformaldehyde
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Embedding:
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Gelatin
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Specimen
S2G:
postnatal day 30
(more )
Specimen
S2G:
(close )
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Genetic Background:
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Not Specified
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Age:
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postnatal day 30
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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Paraformaldehyde
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Embedding:
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Gelatin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS28: cochlea |
Present |
Regionally restricted |
S2G
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Expression is primarily seen in supporting cells.
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