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Gene Expression Data
Assay Details
Assay
Reference: J:74163 El-Amraoui A, et al., Spatiotemporal expression of otogelin in the developing and adult mouse inner ear. Hear Res. 2001 Aug;158(1-2):151-9
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6277928
Gene symbol: Otog
Gene name: otogelin
Antibody: antiserum 7.8
Detection system: Secondary antibody coupled to fluorescein
Assay notes: Either this antibody or another one (antiserum 3.4) was used.
Results
Specimen 1A: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: otocyst epithelium Present Punctate 1A Expressed in various areas of the pluristratified epithelium.

Specimen 1C: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: otocyst epithelium Strong Regionally restricted 1C Increased expression, with the intense signal located in the ventro-medial epithelium close to the sag.

Specimen 1E: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: vestibular component epithelium Present Regionally restricted 1E Expressed in areas where no myosin VIIA-expressing cell was observed.

Specimen 1G: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: cochlea epithelium Present 1G Expressed in the emerging cochlear duct corresponded to the presumptive areas of non-sensory cells.

Specimen 2A: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: saccule Present 2A Expressed in the non-sensory cells of the developing vestibule.
TS21: utricle Present 2A Expressed in the non-sensory cells of the developing vestibule.
TS21: semicircular canal Present Regionally restricted 2A Expressed in crista ampularis epithelium. Expressed in the non-sensory cells of the developing vestibule.

Specimen 2B: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: saccule epithelium Present 2B Expressed in the transitory epithelium.
TS21: utricle epithelium Present 2B Expressed in the transitory epithelium.
TS21: inner ear vestibular component Present Regionally restricted 2B Expressed in the maculae.

Specimen 2C: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: utricle epithelium Present 2C Expression extended beyond the maculae to the surrounding transitory epithelium.
TS23: macula of saccule Present 2C
TS23: macula of utricle Present 2C
TS23: saccule epithelium Present 2C Expression extended beyond the maculae to the surrounding transitory epithelium. Expressed in the roof.

Specimen 2D: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: semicircular canal Strong Regionally restricted 2D Expressed in the crista ampularis and the cupula.

Specimen 2E: postnatal day 60 (more )
Structure Level Pattern Image Note
TS28: crista ampullaris Present 2E
TS28: semicircular canal Present Regionally restricted 2E Expressed in the cupula.

Specimen 2F: postnatal day 60 (more )
Structure Level Pattern Image Note
TS28: crista ampullaris Present Regionally restricted 2F Expressed in the supporting cells and in the transitory epithelium. Expressed in the cupula.

Specimen 2G: postnatal day 60 (more )
Structure Level Pattern Image Note
TS28: utricle epithelium Present 2G Expressed in the supporting cells and in the transitory epithelium. Expressed in the otoconial membrane.

Specimen 2H: postnatal day 60 (more )
Structure Level Pattern Image Note
TS28: utricle epithelium Present 2H Expressed in the supporting cells and in the transitory epithelium. Expressed in the otoconial membrane.

Specimen 3A: postnatal day 0 (more )
Structure Level Pattern Image Note
TS27: macula of utricle Present Widespread 3A Expressed throughout the cell cytoplasm of the supporting cells.

Specimen 3B: postnatal day 8 (more )
Structure Level Pattern Image Note
TS28: macula of utricle Present 3B Gradually decreased expression within the supporting cells following a basal to apical gradient.

Specimen 3C: postnatal day 20 (more )
Structure Level Pattern Image Note
TS28: macula of utricle Present Regionally restricted 3C Restricted to the apical part of the supporting cells, while in the above otoconial membranes, the labeling became broader

Specimen 5A: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: cochlear duct Strong Regionally restricted 5A Expressed in all the non-sensory cells, the interdental cells of the spiral limbus and in the tectorial membrane. Also expressed in Claudius cells, the spiral prominence and Reissner's membrane.
TS24: greater epithelial ridge Present 5A Expressed in the columnar cells.

Specimen 5B: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: tectorial membrane Strong 5B Expressed in the major and minor tectorial membranes.
TS26: organ of Corti Present 5B Expressed in the non-sensory cells, i.e. pillar, Deiter's and Hensen's cells. Also expressed in Claudius cells, the spiral prominence and Reissner's membrane.
TS26: cochlear duct Present Regionally restricted 5B Expressed in the interdental cells of the spiral limbus.
TS26: greater epithelial ridge Present 5B Expressed in the columnar cells.

Specimen 5C: postnatal day 2 (more )
Structure Level Pattern Image Note
TS27: tectorial membrane Strong 5C Expressed in the major and minor tectorial membranes.
TS27: spiral limbus Present 5C Expressed in the interdental cells of the spiral limbus.
TS27: cochlea epithelium Present Regionally restricted 5C Expressed in the columnar cells that form the greater epithelial ridge. Decreased expression in the spiral prominence, the Reissner's membrane, and Claudius cells. Expressed in the pillar cells and Hensen's cells.

Specimen 5D: postnatal day 4 (more )
Structure Level Pattern Image Note
TS28: tectorial membrane Present 5D Expressed in the major and minor tectorial membranes.

Specimen 5E: postnatal day 4 (more )
Structure Level Pattern Image Note
TS28: tectorial membrane Strong 5E
TS28: spiral limbus Present 5E Expressed in the interdental cells of the spiral limbus.

Specimen 5F: postnatal day 6 (more )
Structure Level Pattern Image Note
TS28: tectorial membrane Strong 5F
TS28: cochlea epithelium Trace 5F almost disappeared

Specimen 5G: postnatal day 8 (more )
Structure Level Pattern Image Note
TS28: tectorial membrane Present 5G
TS28: cochlea epithelium Strong Regionally restricted 5G Expressed in Deiter's cells, especially in the third row of these cells that contribute to the formation of the marginal pillars.

Specimen 5H: postnatal day 8 (more )
Structure Level Pattern Image Note
TS28: tectorial membrane Present 5H
TS28: cochlea epithelium Strong Regionally restricted 5H Expressed in Deiter's cells, especially in the third row of these cells that contribute to the formation of the marginal pillars.

Specimen 5I: postnatal day 20 (more )
Structure Level Pattern Image Note
TS28: tectorial membrane Present 5I
TS28: cochlea epithelium Absent 5I

Specimen not shown: embryonic day 17.5 (more )
Structure Level Pattern Image Note
TS25: cochlear duct Present Regionally restricted Not expressed in the formed stria vascularis.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
10/19/2021
MGI 6.17
The Jackson Laboratory