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Gene Expression Data
Assay Details
Assay
Reference: J:211921 McKeown CR, et al., Tropomyosin is required for cardiac morphogenesis, myofibril assembly, and formation of adherens junctions in the developing mouse embryo. Dev Dyn. 2014 Jun;243(6):800-17
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6192673
Gene symbol: Tmod1
Gene name: tropomodulin 1
Results
Specimen 8A/D: embryonic day 8.5 (more )
Note: Double labeled: green - Tmod1; red - Actn2 (assay MGI:6192669).
Structure Level Pattern Image Note
TS13: cardiac muscle tissue Present Regionally restricted 8D , 8A Expression in cardiomyocytes in outer wall of heart in periodic stripes at gaps in F-actin (H-zones) alternating with alpha-actinin stripes at Z-lines in typical striated myofibrils..

Specimen 8E/H: embryonic day 8.5; Tpm1tm1Dfw/Tpm1tm1Dfw (more )
Note: Double labeled: green - Tmod1; red - Actn2 (assay MGI:6192669).
Structure Level Pattern Image Note
TS13: cardiac muscle tissue Present Regionally restricted 8H , 8E Expression in cardiomyocytes in outer wall of heart accumulating in the vicinity of alpha-actinin/F-actin fibrillar structure, but not organized in a periodic pattern.

Specimen 8K: embryonic day 8.5 (more )
Structure Level Pattern Image Note
TS13: cardiac muscle tissue Present Regionally restricted 8K Expression in cardiomyocytes in outer wall of heart in typical striated myofibrils.

Specimen 8O: embryonic day 8.5; Tmod1tm1Vmf/Tmod1tm1Vmf (more )
Structure Level Pattern Image Note
TS13: cardiac muscle tissue Present Regionally restricted 8O Expression in cardiomyocytes in outer wall of heart in large F-actin aggregates.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
11/16/2021
MGI 6.17
The Jackson Laboratory