Gene Expression Data
Assay Details
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Assay
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Reference:
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J:211921
McKeown CR, et al., Tropomyosin is required for cardiac morphogenesis, myofibril assembly, and formation of adherens junctions in the developing mouse embryo. Dev Dyn. 2014 Jun;243(6):800-17
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Assay type:
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Immunohistochemistry
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MGI Accession ID:
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MGI:6192673
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Gene symbol:
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Tmod1
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Gene name:
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tropomodulin 1
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Results
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Specimen
8A/D:
embryonic day 8.5
(more  )
Note: Double labeled: green - Tmod1; red - Actn2 (assay MGI:6192669).
Specimen
8A/D:
(close  )
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Genetic Background:
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involves: C57BL/6J
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Age:
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embryonic day 8.5
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Sex:
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Not Specified
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Type:
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optical section
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Fixation:
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10% Formalin
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Note:
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Double labeled: green - Tmod1; red - Actn2 (assay MGI:6192669).
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| Structure |
Level |
Pattern |
Image |
Note |
| TS13: cardiac muscle tissue |
Present |
Regionally restricted |
8D
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8A
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Expression in cardiomyocytes in outer wall of heart in periodic stripes at gaps in F-actin (H-zones) alternating with alpha-actinin stripes at Z-lines in typical striated myofibrils.
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Specimen
8E/H:
(close )
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Genetic Background:
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involves: 129P2/OlaHsd * C57BL/6J
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Mutant Allele(s):
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Tpm1tm1Dfw/Tpm1tm1Dfw
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Age:
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embryonic day 8.5
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Sex:
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Not Specified
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Type:
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optical section
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Fixation:
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10% Formalin
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Note:
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Double labeled: green - Tmod1; red - Actn2 (assay MGI:6192669).
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| Structure |
Level |
Pattern |
Image |
Note |
| TS13: cardiac muscle tissue |
Present |
Regionally restricted |
8H
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8E
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Expression in cardiomyocytes in outer wall of heart accumulating in the vicinity of alpha-actinin/F-actin fibrillar structure, but not organized in a periodic pattern.
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Specimen
8K:
embryonic day 8.5
(more )
Specimen
8K:
(close )
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Genetic Background:
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involves: C57BL/6J
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Age:
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embryonic day 8.5
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Sex:
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Not Specified
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Type:
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optical section
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Fixation:
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10% Formalin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS13: cardiac muscle tissue |
Present |
Regionally restricted |
8K
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Expression in cardiomyocytes in outer wall of heart in typical striated myofibrils.
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Specimen
8O:
(close )
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Genetic Background:
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involves: 129S7/SvEvBrd * C57BL/6J
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Mutant Allele(s):
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Tmod1tm1Vmf/Tmod1tm1Vmf
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Age:
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embryonic day 8.5
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Sex:
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Not Specified
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Type:
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optical section
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Fixation:
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10% Formalin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS13: cardiac muscle tissue |
Present |
Regionally restricted |
8O
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Expression in cardiomyocytes in outer wall of heart in large F-actin aggregates.
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Analysis Tools