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Gene Expression Data
Assay Details
Assay
Reference: J:211921 McKeown CR, et al., Tropomyosin is required for cardiac morphogenesis, myofibril assembly, and formation of adherens junctions in the developing mouse embryo. Dev Dyn. 2014 Jun;243(6):800-17
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6192670
Gene symbol: Ttn
Gene name: titin
Results
Specimen 6A/D: embryonic day 8.5 (more )
Note: Triple labeled: green - Ttn; blue - Actn2 (assay MGI:6192668); red - F-actin.
Structure Level Pattern Image Note
TS13: cardiac muscle tissue Present Regionally restricted 6A , 6D Expression in cardiomyocytes.

Specimen 6E/H: embryonic day 8.5; Tpm1tm1Dfw/Tpm1tm1Dfw (more )
Note: Triple labeled: green - Ttn; blue - Actn2 (assay MGI:6192668); red - F-actin.
Structure Level Pattern Image Note
TS13: cardiac muscle tissue Present Regionally restricted 6E , 6H Expression in cardiomyocytes.

Specimen 6I/L/M: embryonic day 8.5 (more )
Note: Triple labeled: green - Ttn; blue - Actn2 (assay MGI:6192668); red - F-actin.
Structure Level Pattern Image Note
TS13: cardiac muscle tissue Present Regionally restricted 6I , 6L , 6M Expression at Z-lines of striated myofibrils.

Specimen 6N/Q/R: embryonic day 8.5; Tpm1tm1Dfw/Tpm1tm1Dfw (more )
Note: Triple labeled: green - Ttn; blue - Actn2 (assay MGI:6192668); red - F-actin.
Structure Level Pattern Image Note
TS13: cardiac muscle tissue Present Regionally restricted 6N , 6Q , 6R Expression inconsistently associated with alpha-actinin in F-actin fibrils.

Specimen 6S/V/W: embryonic day 8.5; Tpm1tm1Dfw/Tpm1tm1Dfw (more )
Note: Triple labeled: green - Ttn; blue - Actn2 (assay MGI:6192668); red - F-actin.
Structure Level Pattern Image Note
TS13: cardiac muscle tissue Present Regionally restricted 6W , 6S , 6V Expression inconsistently associated with alpha-actinin in F-actin fibrils.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
01/07/2020
MGI 6.14
The Jackson Laboratory