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Gene Expression Data
Assay Details
Assay
Reference: J:46142 Fuchs M, et al., Differential expression of MAM-subfamily protein tyrosine phosphatases during mouse development. Mech Dev. 1998 Jan;70(1-2):91-109
Assay type: RNA in situ
MGI Accession ID: MGI:5903112
Gene symbol: Ptprk
Gene name: protein tyrosine phosphatase, receptor type, K
Probe: PTPkappa probe1
Probe preparation: Antisense RNA labelled with S35
Visualized with: Autoradiography
Results
Specimen day 8.5 not shown: embryonic day 8.5 (more )
Structure Level Pattern Image Note
TS13: embryo Weak Diffuse

Specimen day 9.5 not shown: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: embryo Weak Diffuse

Specimen 3A/B: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: midbrain Strong 3A/B
TS20: telencephalon Strong 3A/B
TS20: thalamus Strong Regionally restricted 3A/B Abundant expression in dorsal thalamus.
TS20: olfactory epithelium Strong 3A/B
TS20: oropharynx Strong Regionally restricted 3A/B Strong expression in epithelial layers of oropharynx.
TS20: gut epithelium Strong 3A/B
TS20: pancreas Strong 3A/B
TS20: head bone Strong Regionally restricted 3A/B Intense expression in cartilage primordium of nasal bone.
TS20: heart ventricle wall Strong 3A/B
TS20: basal columns Present 3A/B Expression in neural tube and basal plate of grey matter, which is part of mantle layer and corresponds to ventral horn.
TS20: spinal cord ventricular layer Weak Regionally restricted 3A/B Weak expression in ependymal layer of neural tube with some enhancement in upper and lower plate.

Specimen day 12.5 not shown: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: stomach epithelium Strong
TS20: lung Present Diffuse
TS20: metanephros Present Diffuse
TS20: spinal cord Present Regionally restricted Expression restricted to ventral portion of neural tube.

Specimen 3D/E: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: cerebral cortex intermediate zone Strong 3D/E
TS22: cerebral cortex subventricular zone Present 3D/E
TS22: neocortex Present 3D/E
TS22: cortical plate Absent 3D/E
TS22: brain meninges Weak Diffuse 3D/E
TS22: midbrain tegmentum Weak Diffuse 3D/E
TS22: choroid plexus Present 3D/E Expression in cells of choroid plexus, neuroepithelium surrounding fourth ventricle, and in inner ear.
TS22: cochlea Present 3D/E Expression in cells of choroid plexus, neuroepithelium surrounding fourth ventricle, and in inner ear.
TS22: metencephalon Present 3D/E Expression in cells of choroid plexus, neuroepithelium surrounding fourth ventricle, and in inner ear.
TS22: vibrissa follicle Present 3D/E
TS22: lobar bronchus Present Regionally restricted 3D/E Expression predominantly concentrated in the bronchial tree.
TS22: intestine epithelium Strong 3D/E
TS22: physiological umbilical hernia Strong 3D/E
TS22: stomach epithelium Strong 3D/E
TS22: metanephros Present Regionally restricted 3D/E In kidney, expression largely confined to glomerular structures of medullary and cortical region.

Specimen day 14.5 not shown: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: submandibular gland primordium Present
TS22: vertebra Present Regionally restricted Expression in periosteal collars of spinal column.
TS22: peritoneum Present
TS22: pancreas Strong

Specimen day 16.5 not shown: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: embryo Present Regionally restricted Expression pattern at day 16.5 reported to be similar to that of day 14.5.
TS24: cortical plate Weak
TS24: dorsal grey horn Strong
TS24: ventral grey horn Strong

Specimen 3G/H: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: cortical plate Present 3G/H
TS26: cerebral cortex subventricular zone Weak 3G/H Greatly reduced expression in subventricular zone compared to earlier stages.
TS26: inferior colliculus Present 3G/H
TS26: hypothalamus Present Regionally restricted 3G/H Expression in some areas of thalamus and hypothalamus.
TS26: thalamus Present Regionally restricted 3G/H Expression in some areas of thalamus and hypothalamus.
TS26: enamel organ Weak 3G/H
TS26: pituitary gland Strong 3G/H
TS26: submandibular gland Strong 3G/H Increased levels of expression in submandibular glands.
TS26: heart Strong 3G/H
TS26: bronchiole Present 3G/H
TS26: bronchus Present 3G/H
TS26: lung alveolus Present 3G/H
TS26: intestine epithelium Present 3G/H
TS26: stomach epithelium Present 3G/H
TS26: dorsal grey horn Strong 3G/H
TS26: ventral grey horn Strong 3G/H

Specimen day 18.5 not shown: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: nasal cavity epithelium Weak
TS26: nasal septum epithelium Weak
TS26: serous gland epithelial component Weak
TS26: renal cortex Present
TS26: rectum Strong
TS26: uterus Strong

Specimen 6A1/A2: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: midgut epithelium Present Regionally restricted 6A1/A2 Prominent expression in intraperitoneal part of midgut. Expression restricted to epithelium of midgut. No expression in underlying cell layers.

Specimen 6C1/C2: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: metanephros Present Regionally restricted 6C1/C2 In kidney, expression largely confined to glomerular structures of medullary and cortical region.
TS22: adrenal cortex Present Regionally restricted 6C1/C2 Expression in outermost cortex of adrenal gland.

Specimen 6F1/F2: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: submandibular gland Strong Regionally restricted 6F1/F2 Increased levels of expression in submandibular glands. Expression in acinar serous glands.

Specimen 7A1/A2: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: retina outer nuclear layer Present Regionally restricted 7A1/A2 Expression in marginal region of outer nuclear layer of neural retina.

Specimen 7C1/C2: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: pancreas Strong Regionally restricted 7C1/C2 High levels of expression in primordium of pancreas. Expression in acinar serous glands.

Specimen 7E1/E2: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: stomach epithelium Strong 7E1/E2

Specimen 10A/D: postnatal day 4.5 (more )
Structure Level Pattern Image Note
TS28: cerebral cortex Strong Regionally restricted 10A/D High levels of expression in supragranular part of cortical plate. High levels of expression in subplate of central and cingulate cortex.
TS28: cingulate cortex Strong Regionally restricted 10A/D High levels of expression in supragranular part of cortical plate. High levels of expression in subplate of central and cingulate cortex.
TS28: hippocampus CA3 Strong 10A/D
TS28: dentate gyrus Present 10A/D
TS28: piriform cortex Present 10A/D
TS28: thalamic nucleus Present 10A/D
TS28: basal ganglia Absent 10A/D

Specimen 11A/B: postnatal adult (more )
Structure Level Pattern Image Note
TS28: hippocampus CA1 Weak 11A/B
TS28: hippocampus CA2 Weak 11A/B
TS28: dentate gyrus Strong 11A/B
TS28: hippocampus CA3 Strong 11A/B
TS28: cerebellum molecular layer Present 11A/B
TS28: cerebellum white matter Absent 11A/B

Specimen 12A: postnatal adult (more )
Structure Level Pattern Image Note
TS28: dentate gyrus Strong 12A
TS28: hippocampus CA3 Strong 12A
TS28: hippocampus CA1 Weak 12A
TS28: hippocampus CA2 Weak 12A

Specimen 12D: postnatal adult (more )
Structure Level Pattern Image Note
TS28: cerebellum molecular layer Present 12D
TS28: cerebellum white matter Absent 12D


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
01/18/2022
MGI 6.17
The Jackson Laboratory