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Gene Expression Data
Assay Details
Assay
Reference: J:238674 Barrett NA, et al., Mll-AF4 Confers Enhanced Self-Renewal and Lymphoid Potential during a Restricted Window in Development. Cell Rep. 2016 Jul 26;16(4):1039-54
Assay type: Immunohistochemistry
MGI Accession ID: MGI:5824575
Gene symbol: Kmt2a
Gene name: lysine (K)-specific methyltransferase 2A
Results
Specimen 1C: embryonic day 11.5 (more )
Note: Triple labeled: red - Mll1 (Kmt2a); green - Cd34 (assay MGI:5824577); blue - DAPI.
Structure Level Pattern Image Note
TS19: nephric duct, mesonephric portion Present Regionally restricted 1C Expression in mesonephric ducts.
TS19: urogenital ridge Present Regionally restricted 1C Expression in the tips of the urogenital ridges.

Specimen 1C inset: embryonic day 11.5 (more )
Note: Triple labeled: red - Mll1 (Kmt2a); green - Cd34 (assay MGI:5824577); blue - DAPI.
Structure Level Pattern Image Note
TS19: hematopoietic system Present Regionally restricted 1C inset Expression in circulating hematopoietic cells (HC) in the aortic lumen.
TS19: trunk mesenchyme Present Regionally restricted 1C inset Expression in sub-aortic mesenchymal cells.
TS19: sympathetic nervous system Present 1C inset

Specimen 1D: embryonic day 11.5 (more )
Note: Triple labeled: red - Mll1 (Kmt2a); white - ckit (Kit assay MGI:5824578); blue - DAPI.
Structure Level Pattern Image Note
TS19: hematopoietic system Present Regionally restricted 1D Mll1 , 1D (merge) Expression in circulating hematopoietic cells (HC) in the aortic lumen.
TS19: trunk mesenchyme Present Regionally restricted 1D (merge) , 1D Mll1 Expression in sub-aortic mesenchymal cells.
TS19: dorsal aorta Present Regionally restricted 1D Mll1 , 1D (merge) Expression in intra-aortic cluster cells.

Specimen 1E: embryonic day 11.5 (more )
Note: Quadruple labeled: red - Mll1 (Kmt2a); green - Cd34 (assay MGI:5824577); white - ckit (Kit assay MGI:5824578); blue - DAPI.
Structure Level Pattern Image Note
TS19: dorsal aorta Present Regionally restricted 1E (merge) , 1E Mll1 Expression in intra-aortic cluster cells.

Specimen 1F: embryonic day 14.5 (more )
Note: Quadruple labeled: red - Mll1 (Kmt2a); green - Cd34 (assay MGI:5824577); white - ckit (Kit assay MGI:5824578); blue - DAPI.
Structure Level Pattern Image Note
TS22: liver Present 1F (merge) , 1F Mll1

Specimen 1G: embryonic day 12.5 (more )
Note: Triple labeled: red - Mll1 (Kmt2a); green - Cd34 (assay MGI:5824577); blue - DAPI. Triple labeled: red - Mll1 (Kmt2a); green - Cd34 (assay MGI:5824577); blue - DAPI.
Structure Level Pattern Image Note
TS20: chorioallantoic placenta Present Widespread 1G Authors report widespread expression, with cells in and around the major vessels, including the umbilical artery.
TS20: umbilical artery Present 1G


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
08/04/2020
MGI 6.15
The Jackson Laboratory