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Gene Expression Data
Assay Details
Assay
Reference: J:204675 Mandal S, et al., Soluble guanylate cyclase generation of cGMP regulates migration of MGE neurons. J Neurosci. 2013 Oct 23;33(43):16897-914
Assay type: RNA in situ
MGI Accession ID: MGI:5702474
Gene symbol: Gucy1a1
Gene name: guanylate cyclase 1, soluble, alpha 1
Probe: Gucy1A3 cDNA1
Probe preparation: Antisense RNA labelled with digoxigenin
Results
Specimen 1A: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: lateral ganglionic eminence Present Regionally restricted 1A Expressed in subventricular zone.

Specimen 1A': embryonic day 13.5; Del(2Dlx1-Dlx2)1Jlr/Del(2Dlx1-Dlx2)1Jlr (more )
Structure Level Pattern Image Note
TS21: lateral ganglionic eminence Ambiguous 1A' Greatly reduced expression in the lateral ganglionic eminence.

Specimen 1B: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: medial ganglionic eminence Present Regionally restricted 1B Expression was largely restricted to the subventricular zone of the dorsal medial ganglionic eminence. The ventral medial ganglionic eminence had low expression.

Specimen 1B': embryonic day 13.5; Del(2Dlx1-Dlx2)1Jlr/Del(2Dlx1-Dlx2)1Jlr (more )
Structure Level Pattern Image Note
TS21: medial ganglionic eminence Ambiguous Regionally restricted 1B' Greatly reduced expression in the dorsal medial ganglionic eminence.

Specimen 1C: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: medial ganglionic eminence Present Regionally restricted 1C Expression was largely restricted to the subventricular zone of the dorsal medial ganglionic eminence. The ventral medial ganglionic eminence had low expression.

Specimen 1C': embryonic day 13.5; Del(2Dlx1-Dlx2)1Jlr/Del(2Dlx1-Dlx2)1Jlr (more )
Structure Level Pattern Image Note
TS21: medial ganglionic eminence Ambiguous Regionally restricted 1C' Greatly reduced expression in the dorsal medial ganglionic eminence.

Specimen 1D: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: caudal ganglionic eminence Present Regionally restricted 1D Expressed in the subventricular zone.

Specimen 1D': embryonic day 13.5; Del(2Dlx1-Dlx2)1Jlr/Del(2Dlx1-Dlx2)1Jlr (more )
Structure Level Pattern Image Note
TS21: caudal ganglionic eminence Ambiguous 1D' Greatly reduced expression in the caudal medial ganglionic eminence.

Specimen 1E: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: lateral ganglionic eminence Present Regionally restricted 1E Expressed in the lateral ganglionic eminence. More prominently expressed in the subpallial mantle zone, particularly in the striatal neurons.

Specimen 1E': embryonic day 15.5; Del(2Dlx1-Dlx2)1Jlr/Del(2Dlx1-Dlx2)1Jlr (more )
Structure Level Pattern Image Note
TS23: lateral ganglionic eminence Present Regionally restricted 1E' Strongly reduced expression in the subventricular zone, moderately decreased expression in the subpallial mantle zone.

Specimen 1F: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: medial ganglionic eminence Present Regionally restricted 1F Expression was largely restricted to the dorsal medial ganglionic eminence. More prominently expressed in the subpallial mantle zone.

Specimen 1F': embryonic day 15.5; Del(2Dlx1-Dlx2)1Jlr/Del(2Dlx1-Dlx2)1Jlr (more )
Structure Level Pattern Image Note
TS23: medial ganglionic eminence Present Regionally restricted 1F' Strongly reduced expression in the subventricular zone, moderately decreased expression in the subpallial mantle zone.

Specimen 1G: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: medial ganglionic eminence Present Regionally restricted 1G Expression was largely restricted to the dorsal medial ganglionic eminence. The ventral medial ganglionic eminence had low expression.
TS23: globus pallidus Absent 1G

Specimen 1G': embryonic day 15.5; Del(2Dlx1-Dlx2)1Jlr/Del(2Dlx1-Dlx2)1Jlr (more )
Structure Level Pattern Image Note
TS23: medial ganglionic eminence Present Regionally restricted 1G' Strongly reduced expression in the subventricular zone, moderately decreased expression in the subpallial mantle zone.

Specimen 1H: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: caudal ganglionic eminence Present 1H

Specimen 1H': embryonic day 15.5; Del(2Dlx1-Dlx2)1Jlr/Del(2Dlx1-Dlx2)1Jlr (more )
Structure Level Pattern Image Note
TS23: caudal ganglionic eminence Present Regionally restricted 1H' Strongly reduced expression in the subventricular zone, moderately decreased expression in the subpallial mantle zone. Ectopic subpallial expression in a caudoventral region.

Specimen 1I: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: cortical plate Present 1I
TS23: cerebral cortex subventricular zone Present Scattered 1I

Specimen 1I': embryonic day 15.5; Del(2Dlx1-Dlx2)1Jlr/Del(2Dlx1-Dlx2)1Jlr (more )
Structure Level Pattern Image Note
TS23: cortical plate Present 1I'
TS23: cerebral cortex subventricular zone Ambiguous 1I' Expression was nearly eliminated.

Specimen 1J: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: cortical plate Present 1J
TS23: cerebral cortex subventricular zone Present Scattered 1J

Specimen 1J': embryonic day 15.5; Del(2Dlx1-Dlx2)1Jlr/Del(2Dlx1-Dlx2)1Jlr (more )
Structure Level Pattern Image Note
TS23: cortical plate Present 1J'
TS23: cerebral cortex subventricular zone Ambiguous 1J' Expression was nearly eliminated.

Specimen 2A: embryonic day 13.5; Lhx6tm1And/Lhx6+ (more )
Structure Level Pattern Image Note
TS21: lateral ganglionic eminence Present 2A

Specimen 2A': embryonic day 13.5; Lhx6tm1And/Lhx6tm1And (more )
Structure Level Pattern Image Note
TS21: lateral ganglionic eminence Present 2A'

Specimen 2B: embryonic day 13.5; Lhx6tm1And/Lhx6+ (more )
Structure Level Pattern Image Note
TS21: medial ganglionic eminence Present Regionally restricted 2B Expressed in the dorsal medial ganglionic eminence.

Specimen 2B': embryonic day 13.5; Lhx6tm1And/Lhx6tm1And (more )
Structure Level Pattern Image Note
TS21: medial ganglionic eminence Present Regionally restricted 2B' Greatly reduced expression in the dorsal medial ganglionic eminence.

Specimen 2C: embryonic day 13.5; Lhx6tm1And/Lhx6+ (more )
Structure Level Pattern Image Note
TS21: medial ganglionic eminence Present 2C

Specimen 2C': embryonic day 13.5; Lhx6tm1And/Lhx6tm1And (more )
Structure Level Pattern Image Note
TS21: medial ganglionic eminence Present Regionally restricted 2C' Greatly reduced expression in the dorsal medial ganglionic eminence.

Specimen 2D: embryonic day 13.5; Lhx6tm1And/Lhx6+ (more )
Structure Level Pattern Image Note
TS21: caudal ganglionic eminence Present 2D

Specimen 2D': embryonic day 13.5; Lhx6tm1And/Lhx6tm1And (more )
Structure Level Pattern Image Note
TS21: caudal ganglionic eminence Present 2D'

Specimen 2E: embryonic day 15.5; Lhx6tm1And/Lhx6+ (more )
Structure Level Pattern Image Note
TS23: lateral ganglionic eminence Present 2E

Specimen 2E': embryonic day 15.5; Lhx6tm1And/Lhx6tm1And (more )
Structure Level Pattern Image Note
TS23: lateral ganglionic eminence Present 2E'

Specimen 2F: embryonic day 15.5; Lhx6tm1And/Lhx6+ (more )
Structure Level Pattern Image Note
TS23: medial ganglionic eminence Present Regionally restricted 2F Expressed in the dorsal medial ganglionic eminence.

Specimen 2F': embryonic day 15.5; Lhx6tm1And/Lhx6tm1And (more )
Structure Level Pattern Image Note
TS23: medial ganglionic eminence Present Regionally restricted 2F' Greatly reduced expression in the dorsal medial ganglionic eminence.

Specimen 2G: embryonic day 15.5; Lhx6tm1And/Lhx6+ (more )
Structure Level Pattern Image Note
TS23: ganglionic eminence Present 2G

Specimen 2G': embryonic day 15.5; Lhx6tm1And/Lhx6tm1And (more )
Structure Level Pattern Image Note
TS23: ganglionic eminence Present 2G'

Specimen 2H: embryonic day 15.5; Lhx6tm1And/Lhx6+ (more )
Structure Level Pattern Image Note
TS23: caudal ganglionic eminence Present 2H

Specimen 2H': embryonic day 15.5; Lhx6tm1And/Lhx6tm1And (more )
Structure Level Pattern Image Note
TS23: caudal ganglionic eminence Present 2H'


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
11/30/2021
MGI 6.17
The Jackson Laboratory